Dong Yijie, Ban Yating, Zhong Ting, Guo Yijia, Tang Dongyan, Yu Runting, Liu Ke
Author Affiliations: School of Nursing, Sun Yat-sen University, Guangzhou, China (Mrs Dong, Mrs Ban, Mrs Guo, and Dr Liu); Pediatric Hematology Department, Sun Yat-sen Memorial Hospital, Guangzhou, China (Mrs Zhong, Mrs Tang, and Mrs Yu).
Cancer Nurs. 2024 Dec 20. doi: 10.1097/NCC.0000000000001412.
For improved health outcomes, children and adolescents with cancer must maintain physical activity. Individualized physical activity prescription is an effective way to promote physical activity in this group.
We reviewed and meta-analyzed evidence on the effectiveness of individualized physical activity prescriptions for improving physical activity and other health outcomes among children and adolescents with cancer.
Seven databases were searched from inception up to January 2024 for randomized controlled trials. Two researchers independently extracted data and assessed the quality of studies using the Risk-of-Bias tool. Data were pooled into Review Manager 5.3 for data synthesis and subgroup analyses.
Seventeen randomized controlled trials were included. The systematic review summarized the characteristics of recent interventions. Meta-analyses showed that although individualized physical activity prescriptions had no overall effect on physical activity (n = 8 studies), anthropometry and body composition (n = 5), functional capacity (n = 3), quality of life (n = 8), fatigue (n = 3), and self-efficacy (n = 5), they improved cardiovascular fitness (n = 8, P = .02) and muscle strength (n = 8, P = .04). Subgroup analyses showed that studies providing 6-month interventions (P = .003) or such interventions combined with motivational interviewing (P = .002) reported significantly increased physical activity in patients.
Individualized physical activity prescriptions appear to improve cardiovascular fitness and muscle strength in children and adolescents with cancer.
High-quality studies providing long-duration interventions and motivational interviewing are needed for optimal physical activity programs for children and adolescents with cancer. The application of electronic devices should increase the types of physical activities for this group to further improve health outcomes.
为改善健康状况，癌症患儿和青少年必须保持身体活动。个性化身体活动处方是促进该群体身体活动的有效方式。
我们回顾并荟萃分析了关于个性化身体活动处方对改善癌症患儿和青少年身体活动及其他健康状况有效性的证据。
检索了七个数据库，从建库至2024年1月的随机对照试验。两名研究人员独立提取数据，并使用偏倚风险工具评估研究质量。数据汇总到Review Manager 5.3中进行数据合成和亚组分析。
纳入了17项随机对照试验。系统评价总结了近期干预措施的特点。荟萃分析表明，虽然个性化身体活动处方对身体活动（n = 8项研究）、人体测量学和身体成分（n = 5项）、功能能力（n = 3项）、生活质量（n = 8项）、疲劳（n = 3项）和自我效能感（n = 5项）没有总体影响，但它们改善了心血管适能（n = 8项，P = .02）和肌肉力量（n = 8项，P = .04）。亚组分析表明，提供6个月干预措施的研究（P = .003）或此类干预措施与动机性访谈相结合的研究（P = .002）报告称患者的身体活动显著增加。
个性化身体活动处方似乎能改善癌症患儿和青少年的心血管适能和肌肉力量。
为癌症患儿和青少年制定最佳身体活动计划，需要高质量的研究提供长期干预措施和动机性访谈。电子设备的应用应增加该群体的身体活动类型，以进一步改善健康状况。
