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首例与留置装置相关的化脓性关节炎病例报告。

First case report of septic arthritis associated with an indwelling device.

作者信息

Akkaya Samiha, Ozdemir Yusuf Emre, Ensaroglu Esra, Cetin Ergun, Kumbasar Karaosmanoglu Hayat

机构信息

Department of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Department of Internal Medicine, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

出版信息

Future Microbiol. 2025 Feb;20(3):183-188. doi: 10.1080/17460913.2024.2444160. Epub 2024 Dec 20.

DOI:10.1080/17460913.2024.2444160
PMID:39704774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11812362/
Abstract

usually presents with erythrasma, a macular rash, but rarely it can cause extracutaneous infections such as endocarditis, peritonitis, pyelonephritis, and catheter-related bloodstream infections. Here, we present the first case of septic arthritis caused by and a literature review of invasive infections. The diagnosis was confirmed by the patient's clinical findings and microbiological examination of the joint fluid. Considering the patients hemodialysis catheter and the pathogenic nature of the , we strongly suspected a catheter-related infection. Clinical and laboratory follow-ups showed consistent improvement with treatment, characterized by reduced pain, swelling, and localized warmth in the left knee, along with a significant decline in acute-phase reactants. The patient achieved full recovery following a four-week course of antibiotics and catheter removal. Our report emphasizes the importance of not disregarding the isolation of non-diphtheria from appropriately collected sterile samples in symptomatic patients, particularly those with indwelling devices. Based on this case report, clinicians should consider the rare possibility of this microorganism being the cause of septic arthritis.

摘要

通常表现为红癣,一种斑疹,但极少情况下它会引起皮肤外感染,如心内膜炎、腹膜炎、肾盂肾炎以及与导管相关的血流感染。在此,我们报告首例由[具体微生物名称未给出]引起的脓毒性关节炎病例,并对侵袭性[具体微生物名称未给出]感染进行文献综述。通过患者的临床症状及关节液的微生物学检查确诊。考虑到患者的血液透析导管以及[具体微生物名称未给出]的致病特性,我们强烈怀疑是与导管相关的感染。临床和实验室随访显示治疗后病情持续改善,表现为左膝疼痛减轻、肿胀消退、局部发热缓解,同时急性期反应物显著下降。患者在接受为期四周的抗生素治疗及拔除导管后完全康复。我们的报告强调,对于有症状的患者,尤其是有留置装置的患者,从适当采集的无菌样本中分离出非白喉[具体微生物名称未给出]时,不可忽视。基于本病例报告,临床医生应考虑这种微生物作为脓毒性关节炎病因的罕见可能性。

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本文引用的文献

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Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention.血流感染:发病机制与干预机会
Nat Rev Microbiol. 2025 Apr;23(4):210-224. doi: 10.1038/s41579-024-01105-2. Epub 2024 Oct 17.
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Suboptimal bioinformatic predictions of antimicrobial resistance from whole-genome sequences in multidrug-resistant Corynebacterium isolates.多药耐药性 Corynebacterium 分离株全基因组序列对抗菌药物耐药性的生物信息学预测不理想。
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Resistance to Antiseptics and Disinfectants of Planktonic and Biofilm-Associated Forms of .浮游生物和生物膜相关形式的. 对防腐剂和消毒剂的抗性
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