Mohammed Ebrahim, Taye Girma, Assefa Mathewos, Aman Haji, Addissie Adamu, Jemal Ahmedin
Department of Public Health, Adama Hospital Medical College, Adama, Ethiopia.
Department of Epidemiology and Biostatistics, School of Public Health, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.
Cancer Control. 2024 Jan-Dec;31:10732748241310575. doi: 10.1177/10732748241310575.
Cervical cancer (CCa) is the second most common type of cancer and a leading cause of death among adult women in Ethiopia. However, at the moment, there is a lack of evidence that can be generalizable as a whole to the country regarding the uptake of cervical cancer screening.
The aim of this review was to assess the pooled estimated uptake of CCa and to identify the major barriers to cervical cancer screening (CCS) uptake among adult women in Ethiopia.
The review protocol was registered at the International Prospective Register of Systematic Reviews (PROSPERO) with a registration number of CRD42022353954. The data were searched electronically using Google Scholar, PubMed, Medline, and Web of Science search engines. The heterogeneity of the literature was assessed using Cochran's (Q) test and Higgin's and Thomson's (I) statistic. The Rosenthal approach, Fail-safe N method, Egger's test with a -value <0.05, and funnel plot symmetry were used to detect publication bias. Random effect analysis was used to find out the pooled effect size. The Stata 17 software was used to perform analysis.
The pooled estimated uptake of CCS was 13.08% (POR 13.08; 95% CI: 10.24, 15.93; I = 81.93%). Common factors associated with uptake of CCS were adequacy of knowledge (POR = 3.48; 95% CI: 2.74, 4.23; I = 0%), attitudes of women (POR = 3.51; 95% CI: 2.96, 4.07; I = 0%), and perceived susceptibility (POR = 4.03; CI: 2.68, 5.39; I = 46.38%). A slightly high degree of overlap of studies was observed.
The pooled estimated CCS is low. Factors like adequacy of knowledge of CCa, attitudes of women, and perception of susceptibility among women showed a significant association with cervical cancer screening uptake. Creating a platform where women can get adequate and focused information about cervical cancer and screening is crucial.
宫颈癌(CCa)是埃塞俄比亚第二常见的癌症类型,也是成年女性死亡的主要原因。然而,目前缺乏能够作为一个整体推广至该国的关于宫颈癌筛查接受情况的证据。
本综述的目的是评估宫颈癌筛查的合并估计接受率,并确定埃塞俄比亚成年女性接受宫颈癌筛查(CCS)的主要障碍。
该综述方案已在国际前瞻性系统评价注册库(PROSPERO)注册,注册号为CRD42022353954。使用谷歌学术、PubMed、Medline和科学网搜索引擎对数据进行电子检索。使用 Cochr an's(Q)检验以及Higgin's和Thomson's(I)统计量评估文献的异质性。采用罗森塔尔法、失效安全数法、p值<0.05的Egger检验以及漏斗图对称性来检测发表偏倚。采用随机效应分析来确定合并效应量。使用Stata 17软件进行分析。
CCS的合并估计接受率为13.08%(比值比13.08;95%置信区间:10.24,15.93;I² = 81.93%)。与接受CCS相关的常见因素包括知识充足(比值比 = 3.48;95%置信区间:2.74,4.23;I² = 0%)、女性态度(比值比 = 3.51;95%置信区间:2.96,4.07;I² = 0%)以及感知易感性(比值比 = 4.03;置信区间:2.68,5.39;I² = 46.38%)。观察到研究存在一定程度的高度重叠。
CCS的合并估计接受率较低。诸如对宫颈癌知识的充足程度、女性态度以及女性对易感性的认知等因素与宫颈癌筛查接受情况存在显著关联。创建一个女性能够获取关于宫颈癌和筛查的充分且有针对性信息的平台至关重要。