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产前超声诊断及病理确诊的后尿道瓣膜症一例：病例报告

A case of posterior urethral valve diagnosed by ultrasound in antenatal and pathology: A case report.

作者信息

Gao Jinmei, Guan Yunping, Kang Junling, Zhang Wei

机构信息

Department of Ultrasound, Shenyang Maternity and Child Health Hospital, Shenyang, Liaoning Province, China.

Department of Pathology, Shenyang Maternity and Child Health Hospital, Shenyang, Liaoning Province, China.

出版信息

Medicine (Baltimore). 2024 Dec 20;103(51):e40961. doi: 10.1097/MD.0000000000040961.

DOI:10.1097/MD.0000000000040961
PMID:39705458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11666172/
Abstract

RATIONALE

Posterior urethral valve is a rare disease, prenatal diagnosis and prognosis evaluation are particularly important.

PATIENT CONCERNS

A 25-year-old pregnant woman was found enhanced parenchymal echo in both kidneys, subcapsule urinary cyst formation in both kidneys, bladder enlargement of the fetus during prenatal ultrasonography at 25 W + 4 of gestation. It was accompanied by fetal pericardial effusion and oligohydramnios.

DIAGNOSES

Fetal posterior urethral valve.

INTERVENTIONS

After detailed prenatal evaluation, labor was induced and fetal autopsy was performed.

OUTCOMES

Fetal autopsy pathology confirmed the prenatal judgment.

LESSONS

Prenatal ultrasonography can diagnose posterior urethral valve through typical image manifestations and can make a certain judgment for prognosis evaluation.

摘要

理论依据

后尿道瓣膜是一种罕见疾病，产前诊断及预后评估尤为重要。

患者情况

一名25岁孕妇，在妊娠25周+4天进行产前超声检查时发现双肾实质回声增强、双肾包膜下尿囊肿形成，胎儿膀胱增大，伴有胎儿心包积液及羊水过少。

诊断

胎儿后尿道瓣膜。

干预措施

经过详细的产前评估后引产并进行胎儿尸检。

结果

胎儿尸检病理证实产前判断。

经验教训

产前超声可通过典型图像表现诊断后尿道瓣膜，并可对预后评估做出一定判断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/b965d9945618/medi-103-e40961-g010.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/d205c92a8041/medi-103-e40961-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/42e539c8fef7/medi-103-e40961-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/408604539cd9/medi-103-e40961-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/35c227f25309/medi-103-e40961-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/41c168585ca6/medi-103-e40961-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/9146a48b0b03/medi-103-e40961-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7e/11666172/b965d9945618/medi-103-e40961-g010.jpg

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本文引用的文献

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Prune belly syndrome: Approaches to its diagnosis and management.梅干腹综合征：诊断与管理方法
Intractable Rare Dis Res. 2018 Nov;7(4):271-274. doi: 10.5582/irdr.2018.01094.
2
Antenatal staging of congenital lower urinary tract obstruction.先天性下尿路梗阻的产前分期。
Ultrasound Obstet Gynecol. 2019 Apr;53(4):520-524. doi: 10.1002/uog.19172.
3
Ultrasound prenatal diagnosis of typical megacystis, microcolon, intestinal hypoperistalsis syndrome.典型巨膀胱、小结肠、肠蠕动减少综合征的超声产前诊断
Clin Case Rep. 2018 Mar 12;6(5):855-858. doi: 10.1002/ccr3.1481. eCollection 2018 May.
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Fetal bladder outlet obstruction: Embryopathology, in utero intervention and outcome.胎儿膀胱出口梗阻：胚胎病理学、宫内干预及预后
J Pediatr Urol. 2016 Oct;12(5):296-303. doi: 10.1016/j.jpurol.2016.05.047. Epub 2016 Aug 6.
5
Posterior urethral valves and vesicoureteral reflux: can prenatal ultrasonography distinguish between these two conditions in male fetuses?后尿道瓣膜与膀胱输尿管反流：产前超声检查能否区分男性胎儿的这两种情况？
Prenat Diagn. 2016 Sep;36(9):831-7. doi: 10.1002/pd.4868. Epub 2016 Jul 29.
6
Antenatal Determinants of Long-Term Kidney Outcome in Boys with Posterior Urethral Valves.后尿道瓣膜症男孩长期肾脏预后的产前决定因素
Fetal Diagn Ther. 2016;39(3):214-21. doi: 10.1159/000439302. Epub 2015 Sep 17.
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Recovery after relief of fetal urinary obstruction: morphological, functional and molecular aspects.胎儿尿路梗阻解除后的恢复：形态学、功能和分子学方面
Am J Physiol Renal Physiol. 2001 Jul;281(1):F26-37. doi: 10.1152/ajprenal.2001.281.1.F26.