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心内科重症监护病房老年菌血症患者的评估

Evaluation of elderly patients with bacteremia in the cardiology intensive care unit.

作者信息

Doğan Kaya Sibel, Kizmaz Yeşim Uygun, Yiğit Fatih

机构信息

Diseases and Clinical Microbiology Department, Kosuyolu High Specialization Training and Research Hospital, Istanbul, Turkey.

Heart Surgery Department, Kosuyolu High Specialization Training and Research Hospital, Istanbul, Turkey.

出版信息

Medicine (Baltimore). 2024 Dec 20;103(51):e40863. doi: 10.1097/MD.0000000000040863.

Abstract

In this study, the blood culture results of patients aged >65 years who were admitted to the cardiology intensive care unit in a training and research hospital and who had positive blood cultures within the first 48 hours were evaluated. This was a retrospective, observational and nonrandomized study. Patient data at the time of the blood culture were included in the study. Sex, age, length of hospital stay, mortality, Acute Physiology Chronic Health Evaluation II score, laboratory values, and microorganisms grown in blood culture included in the study. Two hundred forty-seven patients, 43.3% of whom were female (n = 107), were included in the study. The median age of the patients was 75 (range 70-83). The mean hospital stay was 5 days (range 3-8). All patients had a median Acute Physiology Chronic Health Evaluation II score of 21 (range 19-23). The overall mortality rate 48.2% (n = 119). The results showed that 49.8% of those died and 50.2% of survivors had positive blood culture results. The most common gram-positive cocci in those died were Staphylococcus hominis (15.6%), Staphylococcus epidermis (14.8%), Enterococcus faecium (9.6%). The most common gram-negative cocci were Escherichia coli (9.6%), Klebsiella pneumoniae (9.6%), Acinetobacter baummanii (1.6%). With an increase in the elderly population, infection management in elderly patients hospitalized in cardiology intensive care units has become increasingly critical.

摘要

在本研究中,对年龄大于65岁、入住一家培训与研究医院心内科重症监护病房且在入院后48小时内血培养结果呈阳性的患者的血培养结果进行了评估。这是一项回顾性、观察性且非随机的研究。血培养时的患者数据被纳入研究。研究内容包括性别、年龄、住院时间、死亡率、急性生理与慢性健康状况评估II(APACHE II)评分、实验室检查值以及血培养中培养出的微生物。共有247例患者纳入研究,其中43.3%为女性(n = 107)。患者的中位年龄为75岁(范围70 - 83岁)。平均住院时间为5天(范围3 - 8天)。所有患者的APACHE II评分中位数为21分(范围19 - 23分)。总体死亡率为48.2%(n = 119)。结果显示,死亡患者中有49.8%血培养结果呈阳性,存活患者中有50.2%血培养结果呈阳性。死亡患者中最常见的革兰氏阳性球菌是霍氏葡萄球菌(15.6%)、表皮葡萄球菌(14.8%)、粪肠球菌(9.6%)。最常见的革兰氏阴性球菌是大肠埃希菌(9.6%)、肺炎克雷伯菌(9.6%)、鲍曼不动杆菌(1.6%)。随着老年人口的增加,心内科重症监护病房老年住院患者的感染管理变得越来越重要。

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