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一种避免心脏停搏液输注并发症的技术:一例使用全身性高钾血症体外循环联合循环停止的病例

A technique avoiding cardioplegia delivery complications: a case using systemic hyperkalemia cardiopulmonary bypass combined with circulatory arrest.

作者信息

Takeichi Tomohisa, Morimoto Yoshihisa, Yamada Akitoshi, Tanaka Takanori

机构信息

Department of Clinical Engineering, Kitaharima Medical Center, 926-250, Ichiba-cho, Ono-shi, Hyogo, 675-1392, Japan.

Department of Cardiovascular Surgery, Kitaharima Medical Center, 926-250, Ichiba-cho, Ono-shi, Hyogo, 675-1392, Japan.

出版信息

J Extra Corpor Technol. 2024 Dec;56(4):207-210. doi: 10.1051/ject/2024027. Epub 2024 Dec 20.

DOI:10.1051/ject/2024027
PMID:39705585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11661784/
Abstract

We conducted a high-risk redo mitral valve replacement through a right mini-thoracotomy without rib spreading (redo-MICS MVR) under systemic hyperkalemia combined with circulatory arrest to circumvent complications associated with cardioplegia delivery. The patient, a 75-year-old man, had a predicted mortality rate of 20%. Initial antegrade cardioplegia successfully induced cardiac arrest, which was administered every 30 min. However, upon infusion of the second dose of cardioplegia, the aortic root pressure was approximately 20 mmHg. Despite multiple attempts to re-cross the clamp, the aortic root pressure did not improve. Consequently, retrograde cardioplegia was considered, but due to significant adhesion of the inferior vena cava, this approach was abandoned. Thus, the procedure was altered to utilize systemic hyperkalemia without aortic cross-clamping (ACC). Given the preoperative transesophageal echocardiography (TEE) diagnosis of mild aortic regurgitation, maintaining a clear surgical field was challenging, necessitating the combination of redo-MVR with circulatory arrest. This case exemplifies the successful management of cardioplegia delivery complications using systemic hyperkalemia and circulatory arrest, resulting in a favorable postoperative recovery for the patient.

摘要

我们在系统性高钾血症合并循环骤停的情况下,通过右胸小切口不撑开肋骨进行了高风险再次二尖瓣置换术(redo-MICS MVR),以规避与心脏停搏液输注相关的并发症。患者为一名75岁男性,预计死亡率为20%。最初的顺行心脏停搏液成功诱导了心脏骤停,每30分钟给药一次。然而,在输注第二剂心脏停搏液时,主动脉根部压力约为20mmHg。尽管多次尝试重新穿过阻断钳,但主动脉根部压力并未改善。因此,考虑采用逆行心脏停搏液,但由于下腔静脉严重粘连,该方法被放弃。于是,手术改为利用无主动脉阻断(ACC)的系统性高钾血症。鉴于术前经食管超声心动图(TEE)诊断为轻度主动脉瓣反流,保持清晰的手术视野具有挑战性,因此需要将再次二尖瓣置换术与循环骤停相结合。该病例例证了使用系统性高钾血症和循环骤停成功处理心脏停搏液输注并发症,使患者术后恢复良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d4/11661784/9d27c12a185e/ject-56-207-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d4/11661784/4a93947e1a09/ject-56-207-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d4/11661784/d282176eed64/ject-56-207-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d4/11661784/9d27c12a185e/ject-56-207-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d4/11661784/4a93947e1a09/ject-56-207-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d4/11661784/d282176eed64/ject-56-207-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d4/11661784/9d27c12a185e/ject-56-207-fig3.jpg

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本文引用的文献

1
Fifth-time redo mitral valve replacement via right thoracotomy under systemic hyperkalemia cardiopulmonary bypass without aortic cross-clamp.全麻下体外循环中高钾血症行右侧开胸第五次二尖瓣置换术,主动脉无阻断。
J Extra Corpor Technol. 2023 Dec;55(4):201-205. doi: 10.1051/ject/2023040. Epub 2023 Dec 15.
2
Minimally Invasive Strategy to Repair Mitral Valve after Repeated Coronary Revascularization: A Case Report and Literature Review.重复冠状动脉血运重建术后二尖瓣修复的微创策略:病例报告及文献综述
J Clin Med. 2023 Nov 15;12(22):7096. doi: 10.3390/jcm12227096.
3
Outcomes of minimally invasive versus conventional sternotomy for redo mitral valve surgery according to Mitral Valve Academic Research Consortium: A systematic review and meta-analysis.
根据二尖瓣外科学术研究联合会的标准,微创与传统胸骨切开术治疗二尖瓣再手术的结果:系统评价和荟萃分析。
Asian J Surg. 2024 Jan;47(1):35-42. doi: 10.1016/j.asjsur.2023.09.001. Epub 2023 Sep 11.
4
Hypothermic Fibrillatory Arrest During Coronary Artery Bypass Grafting in a Man With Calcified Aorta and Ventricular Fibrillation.在一名主动脉钙化和心室颤动的男性患者行冠状动脉旁路移植术中发生低温颤动性停搏。
Tex Heart Inst J. 2021 Sep 1;48(4). doi: 10.14503/THIJ-20-7349.
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Mitral valve reoperation under ventricular fibrillation through right mini-thoracotomy using three-dimensional videoscope.使用三维视频镜经右胸小切口在心室颤动下进行二尖瓣再次手术。
J Cardiothorac Surg. 2013 Apr 12;8:81. doi: 10.1186/1749-8090-8-81.
6
Keeping the heart empty and beating improves preservation of hypertrophied hearts for valve surgery.保持心脏空虚并跳动可改善肥厚心脏在瓣膜手术中的保存效果。
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Immediate and long-term results of mitral prosthetic replacement using a right thoracotomy beating heart technique.采用右胸切口心脏不停跳技术进行二尖瓣人工瓣膜置换术的近期和远期结果。
Eur J Cardiothorac Surg. 2003 Jul;24(1):47-51; discussion 51. doi: 10.1016/s1010-7940(03)00188-x.
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Studies of the effects of ventricular fibrillation on the adequacy of regional myocardial flow. 3. Mechanisms of ischemia.心室颤动对局部心肌血流量充足性影响的研究。3. 缺血机制。
J Thorac Cardiovasc Surg. 1974 Oct;68(4):634-45.