McClave Stephen A, Omer Endashaw M, Lowen Cynthia C, Martindale Robert G
Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Nestlé Nutrition Institute, Bridgewater, New Jersey, USA.
Nutr Clin Pract. 2025 Feb;40(1):26-33. doi: 10.1002/ncp.11260. Epub 2024 Dec 20.
Evidence of poor nutrition status in a patient present on admission to the intensive care unit is associated with worse clinical outcomes than that for a well-nourished patient who becomes critically ill. Diagnosing malnutrition in this setting is fraught with difficulty, though, because elements of nutrition history are hard to obtain, the interpretation of anthropometric parameters is influenced by the disease process and interventions of critical care and the subjectivity of traditional assessment tools lacks precision. Determining the severity of disease drives the initial management and sets priorities in the derivation of the nutrition plan, focusing on strategies that promote survival. Its design should provide safe and effective nutrition support, avoiding aggressive feeding to make up for deficits in the acute phase of critical illness. In time, with resuscitation and stabilization, addressing pre-existing or developing malnutrition will change management and alter the design of the nutrition therapy.
重症监护病房入院时存在营养不良状况的患者,其临床结局比营养良好但后来患危重病的患者更差。然而,在这种情况下诊断营养不良充满困难,因为营养史的相关内容难以获取,人体测量参数的解读受到疾病进程、重症监护干预措施的影响,而且传统评估工具的主观性缺乏精确性。确定疾病的严重程度推动着初始治疗,并为制定营养计划确定优先事项,重点关注促进生存的策略。营养计划的设计应提供安全有效的营养支持,避免在危重病急性期进行激进喂养以弥补营养不足。随着时间推移,通过复苏和病情稳定,解决先前存在的或正在发展的营养不良问题将改变治疗方式并调整营养治疗的设计。