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冠状动脉搭桥术中左前降支内膜剥脱术后左内乳动脉-左前降支吻合口的中期血管造影评估

Mid-term angiographic evaluation of LIMA-LAD anastomoses following LAD endarterectomy in coronary artery bypass grafting.

作者信息

Zahirova Farida, Tel Üstünışık Çiğdem, Arapi Berk, Göksedef Deniz, Ömeroğlu Suat Nail, İpek Gökhan, Balkanay Ozan Onur

机构信息

Clinic of Cardiovascular Surgery, Special Health Care Center, Baku, Azerbaijan.

Department of Cardiovascular Surgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.

出版信息

BMC Cardiovasc Disord. 2024 Dec 20;24(1):726. doi: 10.1186/s12872-024-04416-7.

Abstract

OBJECTIVE

Diffuse coronary artery disease remains a critical issue that heart surgeons continue to research in terms of treatment options. An alternative method applied during coronary bypass surgery to achieve complete revascularization is coronary artery endarterectomy. Since the reliability of this technique and its effects on mortality and morbidity are still debated in the literature. Our objective in conducting this study is to determine the mid-term patency rates in patients who underwent LAD endarterectomy and to explore its future applicability.

MATERIALS AND METHODS

This study reviewed 20 patients who underwent coronary endarterectomy during CABG in our clinic between January 2014 and December 2021. The data, including contrast imaging to check graft patency, were evaluated retrospectively by reviewing hospital archives and patient files. Patients without LAD endarterectomy were excluded from the study.

RESULTS

LAD endarterectomy and patch-plasty were performed on all patients in the study. In 17 patients, the LIMA graft was anastomosed onto the patch applied to the LAD. It was observed that 12 of the grafts anastomosed to the LAD (60%) were patent during a mean follow-up period of 32.8 ± 25.9 months. The average 4-year survival rate was found to be 95%. Perioperative myocardial infarction occurred in 5 patients (25%). There was no need for high-dose inotropic support, IABP, or ECMO in the postoperative period.

CONCLUSION

Coronary artery endarterectomy should be considered a viable option for surgeons to achieve satisfactory revascularization in cases where suitable anastomosis sites on coronary arteries to ensure adequate outflow are not available. Our findings align closely with literature reports indicating that endarterectomy performed on the LAD, with LIMA used as the conduit, leads to promising outcomes.

摘要

目的

弥漫性冠状动脉疾病仍然是一个关键问题,心脏外科医生仍在对其治疗方案进行研究。在冠状动脉搭桥手术中应用的一种实现完全血运重建的替代方法是冠状动脉内膜切除术。由于该技术的可靠性及其对死亡率和发病率的影响在文献中仍存在争议。我们开展这项研究的目的是确定接受左前降支内膜切除术患者的中期通畅率,并探索其未来的适用性。

材料与方法

本研究回顾了2014年1月至2021年12月期间在我们诊所接受冠状动脉内膜切除术的20例患者。通过查阅医院档案和患者病历,对包括用于检查移植血管通畅性的造影成像在内的数据进行回顾性评估。未进行左前降支内膜切除术的患者被排除在研究之外。

结果

本研究中的所有患者均进行了左前降支内膜切除术和补片成形术。在17例患者中,左内乳动脉移植血管吻合至应用于左前降支的补片上。观察到,在平均32.8±25.9个月的随访期内,吻合至左前降支的移植血管中有12例(60%)通畅。平均4年生存率为95%。围手术期心肌梗死发生在5例患者(25%)中。术后无需大剂量的正性肌力支持、主动脉内球囊反搏或体外膜肺氧合。

结论

对于冠状动脉上没有合适的吻合部位以确保足够流出道的情况,冠状动脉内膜切除术应被视为外科医生实现满意血运重建的可行选择。我们的研究结果与文献报道密切一致,表明以左内乳动脉为管道对左前降支进行内膜切除术可带来良好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcb3/11660880/4e893306477b/12872_2024_4416_Fig1_HTML.jpg

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