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简化儿童高血压定义的提议:弥合认知与行动之间的差距。

A proposal to simplify the definition of pediatric hypertension: bridging the gap between perception and action.

作者信息

Yang Lili, Qiao Yanan, Zhao Min, Xi Bo

机构信息

Department of Epidemiology/Department of Maternal, Child and Adolescent Care, School of Public Health, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.

Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.

出版信息

BMC Med. 2024 Dec 20;22(1):596. doi: 10.1186/s12916-024-03825-x.

Abstract

BACKGROUND

The importance of routine hypertension screening in children and adolescents is now well recognized. However, it is often undiagnosed in clinical practice, partly due to the reliance on a complex blood pressure (BP) percentile-based table with hundreds of cutoffs by age, sex, and height.

MAIN TEXT

Many studies have explored simplified tools for screening hypertension in children and adolescents, such as simplified formulas, simplified BP tables by age and sex group, by age group, or by height group, and the BP to height ratio. Nevertheless, validation studies have demonstrated that these simplified tools are prone to yielding many false-positive cases or remain inconvenient to use in primary pediatric care settings and large-scale screening surveys. To address this issue, we propose adopting static BP cutoffs of 120/80 mmHg for children aged 6-12 years and 130/80 mmHg for adolescents aged 13-17 years to simplify the definition of hypertension. Our proposed static BP cutoffs have shown comparable performance to the complex BP percentile-based table in predicting subclinical cardiovascular damage in both childhood and adulthood.

CONCLUSIONS

We recommend using static BP cutoffs (120/80 mmHg for children and 130/80 mmHg for adolescents) to facilitate the screening of pediatric hypertension in clinical practice, thereby bridging the gap between perception and action.

摘要

背景

儿童和青少年常规高血压筛查的重要性现已得到充分认可。然而,在临床实践中,高血压往往未被诊断出来,部分原因是依赖基于复杂血压(BP)百分位数的表格,该表格有数百个按年龄、性别和身高划分的临界值。

正文

许多研究探索了用于筛查儿童和青少年高血压的简化工具,如简化公式、按年龄和性别组、年龄组或身高组划分的简化血压表格以及血压与身高比。然而,验证研究表明,这些简化工具容易产生许多假阳性病例,或者在基层儿科护理环境和大规模筛查调查中使用起来仍然不方便。为了解决这个问题,我们建议采用6至12岁儿童静态血压临界值为120/80 mmHg,13至17岁青少年为130/80 mmHg,以简化高血压的定义。我们提出的静态血压临界值在预测儿童期和成年期亚临床心血管损伤方面表现与基于复杂血压百分位数的表格相当。

结论

我们建议使用静态血压临界值(儿童为120/80 mmHg,青少年为130/80 mmHg),以促进临床实践中儿童高血压的筛查,从而弥合认知与行动之间的差距。

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本文引用的文献

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Hypertension in children and adolescents.儿童和青少年高血压。
Eur Heart J. 2022 Sep 14;43(35):3290-3301. doi: 10.1093/eurheartj/ehac328.
3
Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events.儿童心血管危险因素与成人心血管事件。
N Engl J Med. 2022 May 19;386(20):1877-1888. doi: 10.1056/NEJMoa2109191. Epub 2022 Apr 4.
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Hypertension in adolescents: diagnosis, treatment, and implications.青少年高血压:诊断、治疗及影响。
Lancet Child Adolesc Health. 2021 May;5(5):357-366. doi: 10.1016/S2352-4642(20)30344-8. Epub 2021 Mar 10.

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