Oian P, Omsjø I, Maltau J M, Osterud B
Br J Haematol. 1985 Jan;59(1):133-7. doi: 10.1111/j.1365-2141.1985.tb02973.x.
The thromboplastin activity in blood monocytes from 18 normal third trimester pregnant women has been compared with a group of 20 healthy non-pregnant women. The thromboplastin activity in unstimulated monocytes from the normal pregnant group was on average 40% of the activity in the non-pregnant group (P less than 0.01). In endotoxin stimulated monocytes, the thromboplastin activity was also significantly lower in the pregnant group as compared to the non-pregnant group (P less than 0.001). Fibrinogen and factors V, VII and VIII were significantly higher in the pregnant than in the non-pregnant group, whereas no difference was observed in AT-III, prekallikrein and alpha 2-antiplasmin levels.
对18名孕晚期正常孕妇的血液单核细胞中的促凝血酶原激酶活性与20名健康非孕妇进行了比较。正常孕妇组未受刺激的单核细胞中的促凝血酶原激酶活性平均为非孕妇组活性的40%（P<0.01）。在内毒素刺激的单核细胞中，孕妇组的促凝血酶原激酶活性也显著低于非孕妇组（P<0.001）。孕妇组的纤维蛋白原以及因子V、VII和VIII显著高于非孕妇组，而抗凝血酶III、前激肽释放酶和α2-抗纤溶酶水平未观察到差异。
