Xie Daijun, Li Xu, Teng Fei, Liu Zhongcheng, Yan Zhenxing, Wu Meng, Jiang Jin
Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Arthroscopy. 2025 Aug;41(8):3255-3267. doi: 10.1016/j.arthro.2024.12.015. Epub 2024 Dec 19.
To investigate whether lateral femoral condyle ratio (LFCR) and lateral femoral condyle index (LFCI) were associated with a greater risk of anterior cruciate ligament (ACL) injury and concomitant injuries.
This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was registered on PROSPERO. PubMed, Web of Science, Embase, and the Cochrane Library were searched from inception to April 1, 2024. Studies evaluating the association between LFCR or LFCI and ACL injury were included. The following data were extracted: first author's name, study design, level of evidence, information of participants, radiologic method of measurement, and mean values for LFCR and LFCI. The quality assessment followed the Methodological Index for Non-Randomized Studies tool. The literature search, data extraction, and quality assessment were conducted by 2 authors independently.
A total of 14 studies comprising 2,386 participants were included. Notably, 11 studies explored the association between LFCR and ACL. Six studies showed that the mean LFCR in ACL injury group (range, 62.65%-70.1%) was significantly greater than control group (range, 59.3%-66.8%). Five studies reported that the increased LFCR was associated with a greater risk of concomitant anterolateral ligament injury and meniscal tear. However, 2 studies reported no significant association between LFCR and ACL reconstruction revision, with a mean LFCR ranging from 62.5% to 64.4% in the ACL reconstruction revision group and 62.8% to 64.2% in the primary ACL group. In addition, 2 studies reported that decreased LFCI was associated with a greater risk of ACL injury ranging from 0.60 to 0.78 for the ACL injury group and 0.60 to 0.85 for controls.
Increased LFCR was associated with a greater risk of ACL injury and concomitant anterolateral ligament injuries and meniscal tears. Furthermore, decreased LFCI was associated with a higher risk of ACL injury.
Level III, systematic review of Level III studies.
探讨外侧股骨髁比率（LFCR）和外侧股骨髁指数（LFCI）是否与前交叉韧带（ACL）损伤及合并损伤的较高风险相关。
本系统评价遵循系统评价和Meta分析的首选报告项目指南，并在国际前瞻性系统评价注册库（PROSPERO）上进行了注册。从数据库建库至2024年4月1日，检索了PubMed、科学网、Embase和考克兰图书馆。纳入评估LFCR或LFCI与ACL损伤之间关联的研究。提取了以下数据：第一作者姓名、研究设计、证据水平、参与者信息、放射学测量方法以及LFCR和LFCI的平均值。质量评估采用非随机研究方法学指数工具。文献检索、数据提取和质量评估由两名作者独立进行。
共纳入14项研究，涉及2386名参与者。值得注意的是，11项研究探讨了LFCR与ACL之间的关联。6项研究表明，ACL损伤组的平均LFCR（范围为62.65% - 70.1%）显著高于对照组（范围为59.3% - 66.8%）。5项研究报告称，LFCR升高与合并前外侧韧带损伤和半月板撕裂的风险增加相关。然而，2项研究报告LFCR与ACL重建翻修之间无显著关联，ACL重建翻修组的平均LFCR范围为62.5%至64.4%，初次ACL组为62.8%至64.2%。此外，2项研究报告称，LFCI降低与ACL损伤风险增加相关，ACL损伤组的LFCI范围为0.60至0.78，对照组为0.60至0.85。
LFCR升高与ACL损伤及合并前外侧韧带损伤和半月板撕裂的风险增加相关。此外，LFCI降低与ACL损伤的较高风险相关。
III级，III级研究的系统评价。
