Amamra Amani, Reggami Yassine, Bouasla Ihcene, Benbouzid Houneida, Becheker Imene, Berredjem Hajira
Laboratory of Applied Biochemistry and Microbiology, Department of Biochemistry, Faculty of Sciences, Badji Mokhtar University, Annaba, Algeria.
Department of Natural and Life Sciences, Faculty of Sciences, University August 20, Skikda, Algeria.
Nat Prod Res. 2024 Dec 22:1-10. doi: 10.1080/14786419.2024.2443489.
In this study, phytochemical and biological properties of and leaves, collected in Algeria, were evaluated. The aqueous extract of the studied plants was subjected to phytochemical screening by biochemical analysis and HPLC. The diffusion assay was assessed to investigate the antimicrobial effect against clinical and reference strains. Moreover, we investigated DPPH and FRAP, as well as the haemolytic activity. The results showed abundance in the phytochemical and mineral components. Notably, exhibited the highest DPPH and FRAP values with IC = 1.69 ± 0.67 and IC = 3.20 ± 0.04 mg/g, respectively. The antibacterial activity was better at the concentration of 25 mg/mL, compared to the standard antibiotics. The inhibition zones varied between 8 and 40 mm. The haemolytic activity did not depict any toxicity. The investigated plants exhibited interesting antioxidant and antibacterial properties and may serve as a valuable source for novel antimicrobial drugs.
在本研究中，对采集于阿尔及利亚的[植物名称1]和[植物名称2]叶片的植物化学和生物学特性进行了评估。通过生化分析和高效液相色谱法对所研究植物的水提取物进行了植物化学筛选。采用扩散试验评估对临床菌株和参考菌株的抗菌效果。此外，我们还研究了1,1-二苯基-2-苦基肼自由基清除能力（DPPH）和铁离子还原抗氧化能力（FRAP）以及溶血活性。结果表明，植物化学和矿物质成分丰富。值得注意的是，[植物名称1]表现出最高的DPPH和FRAP值，其半数抑制浓度（IC）分别为1.69±0.67和3.20±0.04毫克/克。与标准抗生素相比，在25毫克/毫升的浓度下抗菌活性更好。抑菌圈在8至40毫米之间变化。溶血活性未显示出任何毒性。所研究的植物表现出有趣的抗氧化和抗菌特性，可能成为新型抗菌药物的宝贵来源。
