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非药物睡眠干预对术后重症监护病房患者谵妄预防及睡眠改善的影响:一项系统评价与网状Meta分析

The Impact of Non-Pharmacological Sleep Interventions on Delirium Prevention and Sleep Improvement in Postoperative ICU Patients: A Systematic Review and Network Meta-Analysis.

作者信息

Li Jiaqi, Fan Yingying, Luo Ruoyu, Yin Na, Wang Yangyang, Jing Jiyong, Zhang Ju

机构信息

Hangzhou Normal University, Department of Nursing, Zhejiang 311121, China.

School of Nursing, Zhejiang Chinese Medical University, Zhejiang 310053, China.

出版信息

Intensive Crit Care Nurs. 2025 Apr;87:103925. doi: 10.1016/j.iccn.2024.103925. Epub 2024 Dec 21.

Abstract

OBJECTIVES

Analyze the effectiveness of different non-pharmacological sleep interventions in preventing delirium among postoperative ICU patients.

RESEARCH METHODOLOGY

We conducted a comprehensive search on PubMed, Cochrane Library, Web of Science, Embase, CINAHL, OpenGrey and reference lists up to May 2024.

SETTING

We systematically searched all randomized controlled trials related to non-pharmacological sleep interventions for the prevention of delirium.

RESULTS

The results of the network meta-analysis showed that, compared to Usual Care, multicomponent interventions are the most effective measures for preventing delirium in postoperative ICU patients (RR = 0.32, 95 % CI = 0.20 to 0.51). This is followed by non-pharmacological sleep interventions aimed at stress relief (RR = 0.60, 95 % CI = 0.41 to 0.89) and circadian rhythm (RR = 0.61, 95 % CI = 0.39 to 0.96). Additionally, non-pharmacological sleep interventions focusing on circadian rhythm demonstrated an improvement in sleep quality among postoperative ICU patients (SMD = -0.99, 95 % CI = -1.88 to -0.11).

CONCLUSIONS

Our study found that multicomponent non-pharmacological sleep interventions are effective in reducing the incidence of delirium in postoperative ICU patients. Furthermore, non-pharmacological interventions focused on circadian rhythm regulation significantly enhance sleep quality among these patients.

IMPLICATIONS FOR CLINICAL PRACTICE

Based on this study, intensive care units and nursing staff have an opportunity to implement the most effective non-pharmacological sleep interventions to prevent delirium and improve sleep quality in postoperative ICU patients. This could contribute to a reduction in the incidence of delirium in postoperative ICU patients.

摘要

目的

分析不同非药物睡眠干预措施对预防术后重症监护病房(ICU)患者谵妄的有效性。

研究方法

我们在PubMed、Cochrane图书馆、科学网、Embase、CINAHL、OpenGrey以及截至2024年5月的参考文献列表中进行了全面检索。

研究背景

我们系统检索了所有与预防谵妄的非药物睡眠干预相关的随机对照试验。

结果

网状Meta分析结果显示,与常规护理相比,多组分干预是预防术后ICU患者谵妄的最有效措施(风险比[RR]=0.32,95%置信区间[CI]=0.20至0.51)。其次是旨在缓解压力的非药物睡眠干预(RR=0.60,95%CI=0.41至0.89)和昼夜节律干预(RR=0.61,95%CI=0.39至0.96)。此外,关注昼夜节律的非药物睡眠干预使术后ICU患者的睡眠质量得到改善(标准化均数差[SMD]=-0.99,95%CI=-1.88至-0.11)。

结论

我们的研究发现,多组分非药物睡眠干预可有效降低术后ICU患者谵妄的发生率。此外,专注于昼夜节律调节的非药物干预可显著提高这些患者的睡眠质量。

对临床实践的启示

基于本研究,重症监护病房和护理人员有机会实施最有效的非药物睡眠干预措施,以预防术后ICU患者的谵妄并改善睡眠质量。这可能有助于降低术后ICU患者谵妄的发生率。

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