Alnajeebi Afnan M, Yahya Rana, Shafie Alaa, Ashour Amal Adnan, Felemban Mohammed Fareed, Tayeb Faris J
Department of Biochemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
Department of Chemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
J Fluoresc. 2024 Dec 22. doi: 10.1007/s10895-024-04070-4.
A simple and highly effective Schiff-base fluorescent chemosensor (S1) was synthesized and characterized by HNMR and fluorescence spectroscopy. The synthesized chemosensor was applied for the selective and sensitive detection of Hg ions. The chemosensor exhibited a strong 'turn-on' fluorescence response in a CHOH/HO (1:9, v/v) solution due to complex formation (S1-Hg) which block photo induce electron transfer (PET). The chemosensor showed significant sensitivity with very low detection limit of 2.0 ppb, making it suitable for trace-level Hg detection. Furthermore, the S1-Hg complex demonstrated excellent antibacterial activity against various Gram-positive and Gram-negative bacterial strains, broadening its utility beyond sensing. This dual-functional system offers significant potential in environmental and biomedical applications.
合成了一种简单且高效的席夫碱荧光化学传感器（S1），并通过核磁共振氢谱（HNMR）和荧光光谱对其进行了表征。所合成的化学传感器用于汞离子的选择性和灵敏检测。由于形成了阻止光诱导电子转移（PET）的配合物（S1-Hg），该化学传感器在甲醇/水（1:9，v/v）溶液中表现出强烈的“开启”荧光响应。该化学传感器具有显著的灵敏度，检测限低至2.0 ppb，适用于痕量汞检测。此外，S1-Hg配合物对多种革兰氏阳性和革兰氏阴性细菌菌株表现出优异的抗菌活性，拓宽了其传感以外的用途。这种双功能体系在环境和生物医学应用中具有巨大潜力。
