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慢性尿潴留中的利尿作用及肾功能恢复

Diuresis and renal functional recovery in chronic retention.

作者信息

Bishop M C

出版信息

Br J Urol. 1985 Feb;57(1):1-5. doi: 10.1111/j.1464-410x.1985.tb08973.x.

Abstract

Fifty-five patients with chronic urinary retention and incipient or actual renal failure were studied. In the majority of patients renal function improved after bladder decompression, irrespective of whether or not a diuresis occurred. Excessive loss of salt and water was rarely a matter of concern and most patients did not require intravenous fluid replacement. Several lost weight and experienced a fall in blood pressure during the period of diuresis without adverse effect upon renal functional recovery. A profound fall in blood pressure occurred in only three patients, all of whom required long-term sodium supplementation. It is concluded that the problem of salt and water loss after bladder decompression in patients with renal failure is exaggerated and difficult to predict. Over-enthusiastic replacement of fluid in strict accordance with output could readily lead to fluid overload and prolongation of the diuretic period. Therefore fluid replacement should be determined by the clinical condition of the patient and measurement of improving renal function with less emphasis on urine output and its electrolyte content.

摘要

对55例慢性尿潴留且伴有早期或实际肾衰竭的患者进行了研究。在大多数患者中,无论是否出现利尿,膀胱减压后肾功能均有所改善。盐和水的过度流失很少成为问题,大多数患者不需要静脉补液。有几位患者在利尿期体重减轻且血压下降,但对肾功能恢复没有不利影响。仅3例患者出现了严重的血压下降,所有这些患者都需要长期补充钠。得出的结论是,肾衰竭患者膀胱减压后盐和水流失的问题被夸大且难以预测。严格按照尿量过度积极地补液很容易导致液体过载和利尿期延长。因此,补液应根据患者的临床状况以及肾功能改善情况来决定,而较少强调尿量及其电解质含量。

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