Li Xiyue, Yu Ximiao, Luo Ruiqi, Wang Xun
Department of Pulmonary and Critical Care Medicine, Jiangnan University Medical Center, Nanjing Medical University (Wuxi No.2 People's Hospital) Wuxi, Jiangsu Province, China.
Department of Clinical Medicine, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu Province, China.
Sci Prog. 2024 Oct-Dec;107(4):368504241305911. doi: 10.1177/00368504241305911.
Bronchial schwannoma is a rare benign tumor traditionally managed through surgical resection. This case report describes a 69-year-old Chinese woman with an asymptomatic bronchial schwannoma incidentally discovered during routine health check-up. Computed tomography (CT) and bronchoscopy revealed a broad-based mass (27 mm × 16 mm) at the right lower lobe bronchus, causing complete obstruction of the dorsal segment and severe stenosis (>80%) of the basal segment. Histopathological and immunohistochemical analyses confirmed the diagnosis of schwannoma. The patient underwent a single-session multimodal bronchoscopic treatment combining cryotherapy, high-frequency electrocoagulation, and laser therapy, with minimal bleeding (<5 ml). Post-intervention evaluation showed a fully patent right lower lobe bronchus, and at 8-month follow-up, CT confirmed complete resolution without tumor recurrence. This case demonstrates that carefully planned bronchoscopic intervention can effectively manage selected cases of bronchial schwannoma while preserving lung function and minimizing procedural risks.
支气管神经鞘瘤是一种罕见的良性肿瘤，传统上通过手术切除进行治疗。本病例报告描述了一名69岁的中国女性，她在常规健康检查中偶然发现了无症状的支气管神经鞘瘤。计算机断层扫描（CT）和支气管镜检查显示右下叶支气管有一个宽基底肿块（27毫米×16毫米），导致背段完全阻塞，基底段严重狭窄（>80%）。组织病理学和免疫组织化学分析证实了神经鞘瘤的诊断。患者接受了一次多模式支气管镜治疗，联合冷冻疗法、高频电凝术和激光治疗，出血极少（<5毫升）。干预后评估显示右下叶支气管完全通畅，在8个月的随访中，CT证实肿瘤完全消退，无复发。本病例表明，精心规划的支气管镜干预可以有效地治疗某些支气管神经鞘瘤病例，同时保留肺功能并将手术风险降至最低。
