Knudsen Hannah K, Andrews-Higgins Shaquita, Back-Haddix Sandra, Lofwall Michelle R, Fanucchi Laura, Walsh Sharon L
University of Kentucky.
Res Sq. 2024 Dec 12:rs.3.rs-5440415. doi: 10.21203/rs.3.rs-5440415/v1.
Underutilization of medications for opioid use disorder (MOUD), which reflects the limited number of patients initiating treatment and being retained in treatment, remains a persistent barrier to addressing the opioid epidemic. Using an adapted PRISM (Practical, Robust Implementation and Sustainability Model) framework, this study describes multi-level barriers and facilitators to expanding MOUD as part of the HEALing (Helping to End Addiction Long-term) Communities Study in Kentucky (HCS-KY).
Cross-sectional small group and individual semi-structured interviews were conducted with 60 employees representing 30 MOUD agencies in eight Kentucky counties from December 2022 to June 2023. A deductive-dominant approach to interviewing, with all interviews recorded and transcribed. Using a codebook informed by the adapted PRISM framework, a directed consensus-based approach to coding and thematic analysis was used.
Although some agencies had a fairly static number of patients, most described recent experiences with modestgrowth in MOUD census and the ability to provide same day/next day MOUD. Multi-level factors, includingorganizational, patient-level, and community characteristics and perspectives, were perceived to impact MOUDcensus. Organizational characteristics impacting growth included the physical space of the clinic and staffing. Organizational policies in some agencies constrained treatment retention, while other agencies implementedinnovations to better meet patients' needs. Patients often encountered numerous challenges to treatmentinitiation and retention, including limited access to transportation, technology, safe and stable housing, and childcare. These patient-level barriers often reflected community characteristics, while community stigma alsoimpeded MOUD growth.
These qualitative data revealed that some degree of growth in MOUD has occurred, but multi-level barriers are impeding further increases in treatment initiation and retention. Some barriers likely require policy changes related to financing and regulation, while other barriers require community-level efforts to decrease stigma and greater community investment in infrastructure, such as transportation and housing.
ClinicalTrials.gov, NCT04111939. Registered 30 September 2019.
阿片类物质使用障碍药物(MOUD)的利用不足反映了开始治疗并持续接受治疗的患者数量有限,这仍然是应对阿片类药物流行的一个长期障碍。本研究采用适应性PRISM(实用、稳健实施和可持续性模型)框架,描述了作为肯塔基州HEALing(帮助长期戒除成瘾)社区研究(HCS-KY)一部分扩大MOUD的多层次障碍和促进因素。
2022年12月至2023年6月,对代表肯塔基州8个县30个MOUD机构的60名员工进行了横断面小组和个人半结构化访谈。采用以演绎为主的访谈方法,所有访谈均进行录音和转录。使用由适应性PRISM框架提供信息的编码手册,采用基于共识的定向编码和主题分析方法。
虽然一些机构的患者数量相当稳定,但大多数机构描述了近期MOUD普查适度增长以及提供当日/次日MOUD的能力。包括组织、患者层面以及社区特征和观点在内的多层次因素被认为会影响MOUD普查。影响增长的组织特征包括诊所的物理空间和人员配备。一些机构的组织政策限制了治疗的持续,而其他机构实施了创新措施以更好地满足患者需求。患者在开始治疗和持续治疗方面经常遇到诸多挑战,包括交通、技术、安全稳定住房和儿童保育方面的获取有限。这些患者层面的障碍往往反映了社区特征,而社区污名也阻碍了MOUD的增长。
这些定性数据表明MOUD已出现一定程度的增长,但多层次障碍阻碍了治疗开始和持续治疗的进一步增加。一些障碍可能需要与融资和监管相关的政策变革,而其他障碍则需要社区层面努力减少污名,并增加对交通和住房等基础设施的社区投资。
ClinicalTrials.gov,NCT04111939。2019年9月30日注册。