Ratwatte Seshika, Celermajer David S
Department of Cardiology, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
University of Sydney, Faculty of Medicine and Health, Sydney, NSW, Australia.
Int J Cardiol Congenit Heart Dis. 2024 Jul 31;17:100534. doi: 10.1016/j.ijcchd.2024.100534. eCollection 2024 Sep.
Pulmonary hypertension (PH) is a serious potential complication of some congenital heart diseases (CHDs). PH encompasses a range of diseases which may be idiopathic or inherited, or secondary to cardiac, respiratory, systemic or thromboembolic conditions, amongst others. Our increasing understanding of the normal ranges of pulmonary haemodynamics, as well as evidence supporting the benefits of early treatment, has resulted in a number of recent revisions to the haemodynamic definition of PH. In this Review Article, we report on the recent updates to haemodynamic definitions and classification of PH, as reflected in the 2022 Pulmonary Hypertension Guidelines and particularly focus on the CHD related sub-type of PH, where the aetiology is often multi-factorial.
肺动脉高压（PH）是某些先天性心脏病（CHD）的一种严重潜在并发症。PH包括一系列疾病，这些疾病可能是特发性的或遗传性的，或者继发于心脏、呼吸、全身或血栓栓塞性疾病等。我们对肺血流动力学正常范围的认识不断增加，以及支持早期治疗益处的证据，导致了近期对PH血流动力学定义的一些修订。在这篇综述文章中，我们报告了PH血流动力学定义和分类的最新更新，如2022年肺动脉高压指南所反映的那样，并特别关注与CHD相关的PH亚型，其病因通常是多因素的。
