Kopycka-Kedzierawski Dorota T, Ragusa Patricia G, Feng Changyong, Flint Kim, Watson Gene E, Wong Cynthia L, Gill Steven R, Billings Ronald J, O'Connor Thomas G
Department of Oral and Craniofacial Sciences, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, United States.
Department of Biostatistics and Computational Biology and Department of Anesthesiology and Perioperative Medicine, University of Rochester, Rochester, NY, United States.
Front Pediatr. 2024 Dec 6;12:1478302. doi: 10.3389/fped.2024.1478302. eCollection 2024.
To examine the social determinants of early childhood caries (ECC), one of the greatest public health risks affecting children, and examine alternative pathways of influence.
A physically healthy, socio-demographically high-risk sample of initially caries-free children, aged 1-4 years, was prospectively studied for 2 years. At 6-month intervals, assessments were made of caries presence from a standard dental exam; oral microbiology was assayed from saliva samples; oral hygiene behaviors and psychological and psychosocial risk exposure were derived from interviews and questionnaires.
189 children were enrolled; ECC onset occurred in 48 children over the 2-year study period. A composite measure of psychosocial risk was significantly associated with ECC onset over the course of the study (1.57, 95% CI 1.12-2.20, < .001) and significantly associated with multiple risks for ECC, including poor diet/feeding (.92; 95% CI. 22-1.61, < .01), poor oral hygiene (.39; 95% CI .09-.68), < .05), and higher concentrations (.96; 95% CI .43-1.49, < .001). Multivariable regression analyses provided indirect support for the hypothesis that psychosocial risk exposure predicts ECC onset via behavioral and oral hygiene pathways.
The study provides novel evidence that psychosocial factors influence many of the purported risks for ECC and strong evidence that there are social and psychological determinants of ECC onset.
研究幼儿龋齿(ECC)这一影响儿童的重大公共卫生风险的社会决定因素,并探讨其他影响途径。
对1 - 4岁最初无龋齿的身体健康、社会人口统计学特征为高风险的儿童样本进行为期2年的前瞻性研究。每隔6个月,通过标准牙科检查评估龋齿情况;从唾液样本中检测口腔微生物学;通过访谈和问卷得出口腔卫生行为以及心理和社会心理风险暴露情况。
共招募了189名儿童;在2年的研究期内,48名儿童出现了ECC。在研究过程中,社会心理风险的综合指标与ECC发病显著相关(1.57,95%置信区间1.12 - 2.20,P <.001),并且与ECC的多种风险显著相关,包括不良饮食/喂养(.92;95%置信区间.22 - 1.61,P <.01)、不良口腔卫生(.39;95%置信区间.09 -.68,P <.05)以及更高浓度(.96;95%置信区间.43 - 1.49,P <.001)。多变量回归分析为社会心理风险暴露通过行为和口腔卫生途径预测ECC发病这一假设提供了间接支持。
该研究提供了新的证据,表明社会心理因素影响了许多所谓的ECC风险,并有强有力的证据表明ECC发病存在社会和心理决定因素。