接受治疗的妇科癌症患者缺铁性贫血的患病率：一项双机构回顾性研究。

Prevalence of Iron Deficiency Anemia in Gynecological Cancer Patients Undergoing Treatment: A Two-Institution Retrospective Study.

作者信息

Yagi Taro, Kinose Yasuto, Koizumi Mai, Iwamiya Tadashi, Ito Futa, Kubota Satoshi, Sawada Kenjiro, Kimura Tadashi, Takemura Masahiko, Morishige Ken-Ichirou

机构信息

Department of Obstetrics and Gynecology, Osaka General Medical Center, Osaka, JPN.

Department of Obstetrics and Gynecology, Graduate School of Medicine Faculty of Medicine, Osaka University, Suita, JPN.

出版信息

Cureus. 2024 Nov 21;16(11):e74163. doi: 10.7759/cureus.74163. eCollection 2024 Nov.

DOI:10.7759/cureus.74163

PMID:39712704

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11663040/

Abstract

BACKGROUND

Anemia in patients with cancer negatively affects their quality of life and cancer outcomes. However, most patients with chemotherapy-induced anemia (CIA) are not appropriately evaluated or treated, and the prevalence of iron deficiency anemia (IDA) in CIA remains unclear.

METHODS

We retrospectively reviewed the electronic records of patients with gynecological cancer in two tertiary hospitals, between March 2023 and July 2023, and evaluated their anemia status.

RESULTS

We identified 54 patients with CIA, and IDA was found in 74% (40/54) of patients with CIA, including 4% (2/54) with absolute iron deficiency (transferrin saturation (TSAT) < 20% and ferritin < 30 ng/mL), 63% (34/54) with functional iron deficiency (TSAT < 50% and 30 ng/mL < ferritin < 500 ng/mL), and 7% (4/54) with possible functional iron deficiency (TSAT < 50% and 500 ng/mL < ferritin < 800 ng/mL).

CONCLUSIONS

We found that 74% of patients with CIA under gynecologic cancer treatments were IDA in this study.

摘要

背景

癌症患者的贫血会对其生活质量和癌症治疗结果产生负面影响。然而，大多数化疗所致贫血（CIA）患者未得到适当评估或治疗，CIA中铁缺乏性贫血（IDA）的患病率仍不清楚。

方法

我们回顾性分析了2023年3月至2023年7月期间两家三级医院妇科癌症患者的电子病历，并评估了他们的贫血状况。

结果

我们确定了54例CIA患者，其中74%（40/54）的CIA患者存在IDA，包括4%（2/54）的绝对铁缺乏（转铁蛋白饱和度（TSAT）<20%且铁蛋白<30 ng/mL）、63%（34/54）的功能性铁缺乏（TSAT<50%且30 ng/mL<铁蛋白<500 ng/mL）以及7%（4/54）的可能功能性铁缺乏（TSAT<50%且500 ng/mL<铁蛋白<800 ng/mL）。