Gu Jialin, Zhang Hongqun, Qian Kang, Ye Xunwen, Wu Guolin
Department of TCM, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, People's Republic of China.
Hunan Engineering Research Center of TCM Real-World Clinical Practice, The First Affiliated Hospital of Hunan University of Medicine, Huaihua, Hunan, 418000, People's Republic of China.
Int J Womens Health. 2024 Dec 17;16:2157-2171. doi: 10.2147/IJWH.S496718. eCollection 2024.
OBJECTIVE: Obesity has become a significant public health concern, strongly linked to various diseases, particularly gynecologic and breast cancers. This bibliometric review aims to analyze global research trends on overweight women, particularly those with gynecologic and breast cancers, to identify research hotspots, key contributors, and emerging areas of study. METHODS: A comprehensive bibliometric analysis was conducted using the Web of Science Core Collection (WoSCC) database, covering the period from January 2013 to September 2024. Articles were screened and analyzed using tools such as VOSviewer and Biblioshiny platform, with metrics including publication volume, citation analysis, and co-authorship networks. Key areas of focus were global research trends, leading countries, institutions, authors, journals, and keyword analysis. RESULTS: A total of 1452 publications were analyzed. Research activity on the association between obesity and gynecologic/breast cancer has steadily increased, with the United States leading in publications and citations, followed by China and Italy. Core journals included Breast Cancer Research and Treatment and Gynecologic Oncology. Key research areas identified through keyword analysis include the relationship between body mass index (BMI) and cancer risk, survival rates in cancer patients, physical activity, and the role of adipose tissue inflammation in tumor progression. Emerging topics include extracellular vesicles and cancer-associated fibroblasts. CONCLUSION: Global research on the relationship between obesity and female-specific cancers has shown significant growth. The findings highlight BMI, survival, and physical activity as central themes. Future research should explore the molecular mechanisms linking obesity to cancer and evaluate weight loss interventions for cancer prevention and treatment.
目的:肥胖已成为一个重大的公共卫生问题,与多种疾病密切相关,尤其是妇科癌症和乳腺癌。本文献计量学综述旨在分析全球关于超重女性,特别是患有妇科癌症和乳腺癌女性的研究趋势,以确定研究热点、主要贡献者和新兴研究领域。 方法:使用科学网核心合集(WoSCC)数据库进行了全面的文献计量学分析,涵盖2013年1月至2024年9月期间。使用VOSviewer和Biblioshiny平台等工具对文章进行筛选和分析,指标包括发表量、引文分析和共同作者网络。重点关注的关键领域包括全球研究趋势、主要国家、机构、作者、期刊和关键词分析。 结果:共分析了1452篇出版物。关于肥胖与妇科/乳腺癌之间关联的研究活动稳步增加,美国在发表量和引文方面领先,其次是中国和意大利。核心期刊包括《乳腺癌研究与治疗》和《妇科肿瘤学》。通过关键词分析确定的关键研究领域包括体重指数(BMI)与癌症风险之间的关系、癌症患者的生存率、体育活动以及脂肪组织炎症在肿瘤进展中的作用。新兴主题包括细胞外囊泡和癌症相关成纤维细胞。 结论:全球关于肥胖与女性特定癌症之间关系的研究有显著增长。研究结果突出了BMI、生存率和体育活动作为核心主题。未来的研究应探索将肥胖与癌症联系起来的分子机制,并评估减肥干预措施对癌症预防和治疗的效果。
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