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动脉调转术:一项外科学上的重大成功,但面临长期管理挑战。

Arterial switch operation: A surgical triumph with long-term management challenges.

作者信息

Ladouceur Magalie, Ruperti-Repilado Francisco Javier, Rutz Tobias

机构信息

Department of Cardiology, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva, Switzerland.

Department of Cardiology, University Hospital of Basel, Basel, Switzerland.

出版信息

Int J Cardiol Congenit Heart Dis. 2023 Dec 8;15:100487. doi: 10.1016/j.ijcchd.2023.100487. eCollection 2024 Mar.

Abstract

Since the late 1980s, the standard approach for treating D-transposition of the great arteries has been the arterial switch operation (ASO), replacing the Mustard/Senning procedure. Although ASO has shown impressive long-term survival rates, recent case series have revealed late complications such as neoaortic dilation and coronary artery stenosis. New findings emphasize the need for comprehensive evaluation of coronary risk and a deeper understanding of the mechanisms leading to coronary artery stenosis and myocardial ischemia over the long term. Computed tomography angiography (CTA) has unveiled a notable prevalence of abnormal coronary arteries with potential risk of stenosis and myocardial ischemia. Moreover, the progressive dilation of the neoaortic root and the potential for valve regurgitation necessitating intervention warrant serial imaging follow-up. Considering the radiation risks associated with CTA, magnetic resonance imaging emerges as a preferred modality for post-ASO patient assessment. Ongoing research in this field holds the promise of developing improved diagnostic and therapeutic strategies for these patients, thereby enhancing their long-term care.

摘要

自20世纪80年代末以来,治疗大动脉D型转位的标准方法一直是动脉调转手术(ASO),取代了Mustard/Senning手术。尽管ASO已显示出令人印象深刻的长期生存率,但最近的病例系列研究揭示了诸如新主动脉扩张和冠状动脉狭窄等晚期并发症。新的研究结果强调了对冠状动脉风险进行全面评估的必要性,以及对导致冠状动脉狭窄和长期心肌缺血的机制有更深入的了解。计算机断层扫描血管造影(CTA)已揭示出具有狭窄和心肌缺血潜在风险的异常冠状动脉的显著患病率。此外,新主动脉根部的渐进性扩张以及需要干预的瓣膜反流可能性,使得有必要进行系列成像随访。考虑到与CTA相关的辐射风险,磁共振成像成为ASO术后患者评估的首选方式。该领域正在进行的研究有望为这些患者开发出改进的诊断和治疗策略,从而加强他们的长期护理。

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