Drakopoulou Maria, Nyktari Evangelia, Apostolos Anastasios, Sideris Skevos, Kordalis Athanasios, Oikonomou Georgios, Tsioufis Konstantinos, Toutouzas Konstantinos, Gatzoulis Konstantinos
First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece.
Int J Cardiol Congenit Heart Dis. 2022 Jul 13;9:100409. doi: 10.1016/j.ijcchd.2022.100409. eCollection 2022 Sep.
Among the most feared sequelae of repaired Tetralogy of Fallot (TOF) are ventricular arrhythmias and sudden cardiac death (SCD) [1]. The presence of pulmonary regurgitation as a potential risk factor for arrhythmias has sparked interest in a more aggressive strategy for reoperation in TOF patients and chronic pulmonary regurgitation. Although this strategy was initially suggested to be protective against the development of ventricular arrhythmias, timely pulmonary valve replacement (PVR) alone, does not appear to abort the SCD risk as myocardial fibrosis, a clear arrhythmic substrate remains. In this case, we present arrhythmia risk stratification and management of a patient with repaired ToF and concomitant pulmonary regurgitation.
法洛四联症（TOF）修复术后最令人担忧的后遗症是室性心律失常和心源性猝死（SCD）[1]。肺反流作为心律失常的潜在危险因素，引发了人们对TOF患者再次手术和慢性肺反流采取更积极策略的兴趣。尽管最初认为该策略可预防室性心律失常的发生，但仅及时进行肺动脉瓣置换（PVR）似乎并不能消除SCD风险，因为心肌纤维化这一明确的心律失常基质仍然存在。在此，我们介绍了一名TOF修复术后合并肺反流患者的心律失常风险分层及管理。
