α糖脂调控自然杀伤T细胞（NKT细胞）的T细胞受体（TCR）。
The α glycolipid rules the NKT cell TCR.
作者信息
Kronenberg Mitchell, Ascui Gabriel
机构信息
La Jolla Institute for Immunology , La Jolla, CA, USA.
Department of Molecular Biology, University of California San Diego, La Jolla, CA, USA.
出版信息
J Exp Med. 2025 Feb 3;222(2). doi: 10.1084/jem.20242099. Epub 2024 Dec 23.
In this issue of JEM, Hosono et al. (https://doi.org/10.1084/jem.20240728) characterize a putative self- glycolipid that engages the iNKT cell TCR when bound to CD1d. The expression and distribution of this compound helps to explain some of the unusual properties of invariant NKT cells.
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