Santibáñez Sonia, Ramos-Rincón José Manuel, Santibáñez Paula, Cervera-Acedo Cristina, Sanjoaquín Isabel, de Arellano Encarnación Ramírez, Guillén Sara, Del Carmen Lozano María, Llorente Marta, Puerta-Peña Mario, Bularca Elena Aura, González-Praetorius Alejandro, Escribano Isabel, Sánchez Lorenzo, Ibarra Valvanera, Alba Jorge, Palomar Ana M, Beltrán Antonio, Portillo Aránzazu, Oteo José A
Emerg Infect Dis. 2025 Jan;31(1):18-26. doi: 10.3201/eid3101.240151.
Rickettsia sibirica mongolitimonae is an emerging cause of tickborne rickettsiosis. Since the bacterium was first documented as a human pathogen in 1996, a total of 69 patients with this infection have been reported in the literature. Because of the rising rate of R. sibirica mongolitimonae infection cases, we evaluated the epidemiologic and clinical features of 29 patients who had R. sibirica mongolitimonae infections confirmed during 2007-2024 at the Center for Rickettsiosis and Arthropod-Borne Diseases, the reference laboratory of San Pedro University Hospital-Center for Biomedical Research of La Rioja, Logroño, Spain. We also reviewed all cases published in the literature during 1996-2024, evaluating features of 94 cases of R. sibirica mongolitimonae infection (89 in Europe, 4 in Africa, and 1 in Asia). Clinicians should consider R. sibirica mongolitimonae as a potential causative agent of rickettsiosis, and doxycycline should be administered promptly to avoid clinical complications.
西伯利亚立克次体蒙古亚种是蜱传立克次体病的一种新兴病因。自1996年该细菌首次被记录为人类病原体以来，文献中共报道了69例这种感染的患者。由于西伯利亚立克次体蒙古亚种感染病例的发生率不断上升，我们评估了2007年至2024年期间在西班牙洛格罗尼奥拉里奥哈圣佩德罗大学医院生物医学研究中心立克次体病和节肢动物传播疾病参考实验室确诊感染西伯利亚立克次体蒙古亚种的29例患者的流行病学和临床特征。我们还回顾了1996年至2024年期间文献中发表的所有病例，评估了94例西伯利亚立克次体蒙古亚种感染病例的特征（欧洲89例，非洲4例，亚洲1例）。临床医生应将西伯利亚立克次体蒙古亚种视为立克次体病的潜在病原体，并应立即给予强力霉素以避免临床并发症。
