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The complex role of protocadherin-19 in brain function: a focus on the oxytocin system.

作者信息

Mazzoleni Sara, Busnelli Marta, Bassani Silvia

机构信息

CNR Institute of Neuroscience, Vedano al Lambro, Italy (Mazzoleni S, Busnelli M, Bassani S).

NeuroMi Milan Center for Neuroscience, Milan, Italy (Busnelli M, Bassani S).

出版信息

Neural Regen Res. 2025 Nov 1;20(11):3211-3212. doi: 10.4103/NRR.NRR-D-24-00847. Epub 2024 Oct 22.

DOI:10.4103/NRR.NRR-D-24-00847
PMID:39715087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11881728/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43d3/11881728/f3b6d6ebed96/NRR-20-3211-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43d3/11881728/f3b6d6ebed96/NRR-20-3211-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43d3/11881728/f3b6d6ebed96/NRR-20-3211-g001.jpg

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Front Neurosci. 2023 Mar 14;17:1026939. doi: 10.3389/fnins.2023.1026939. eCollection 2023.
2
Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression.条件性 PCDH19 杂合表达敲除小鼠模型中神经元网络活动和连接受损。
Mol Psychiatry. 2024 Jun;29(6):1710-1725. doi: 10.1038/s41380-023-02022-1. Epub 2023 Mar 30.
3
in Males: Are Hemizygous Variants Linked to Autism?
在男性中:半合子变异与自闭症有关吗?
Genes (Basel). 2023 Feb 27;14(3):598. doi: 10.3390/genes14030598.
4
The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes.癫痫相关蛋白 PCDH19 经 NMDA 受体依赖性蛋白水解切割,调节即刻早期基因的表达。
Cell Rep. 2022 May 24;39(8):110857. doi: 10.1016/j.celrep.2022.110857.
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A standardized patient-centered characterization of the phenotypic spectrum of PCDH19 girls clustering epilepsy.PCDH19 女孩聚类性癫痫表型谱的以患者为中心的标准化特征描述。
Transl Psychiatry. 2020 May 4;10(1):127. doi: 10.1038/s41398-020-0803-0.
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