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直接前路全髋关节置换术后的结果:一项当代多中心研究

Outcomes Following Direct Anterior Approach Total Hip Arthroplasty: A Contemporary Multicenter Study.

作者信息

Wilson Jacob M, Hadley Matthew L, Larson Dirk, Ledford Cameron K, Bingham Joshua S, Wyles Cody C, Taunton Michael J

机构信息

Department of Orthopedic Surgery, Emory University, Atlanta, Georgia.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

J Bone Joint Surg Am. 2025 Feb 19;107(4):356-363. doi: 10.2106/JBJS.24.00132. Epub 2024 Dec 23.

Abstract

BACKGROUND

The direct anterior approach (DAA) is a popular approach for primary total hip arthroplasty (THA). However, the contemporary outcomes for DAA THA need further elucidation. Therefore, we aimed to describe implant survivorship, complications, and clinical outcomes after DAA THA.

METHODS

From our multi-institutional total joint registry, 3,184 patients who had undergone 3,698 primary DAA THA between 2010 and 2019 were identified. The identified patients had a mean age of 65 years and a mean body mass index (BMI) of 29 kg/m 2 , and 53% of patients were female. The indications for revision and reoperation and the incidence of complications were collected and analyzed. Potential risk factors, including age, sex, BMI, and high-volume compared with low-volume operating surgeons, were examined. Descriptive statistics and Kaplan-Meier survivorship with Cox regression analyses were performed.

RESULTS

At 10 years following primary DAA THA, the cohort had 96% (95% confidence interval [CI], 95% to 98%) survivorship free of any revision and 94% (95% CI, 92% to 96%) survivorship free of any reoperation. The leading indications for revision were periprosthetic joint infection (PJI) (n = 24; 5-year cumulative incidence, 0.93% [95% CI, 0.6% to 1.5%]), periprosthetic fracture (n = 20; 5-year cumulative incidence, 0.62% [95% CI, 0.4% to 1.0%]), and aseptic loosening (n = 14; 11 femoral, 3 acetabular; 5-year cumulative incidence, 0.84% [95% CI, 0.5% to 1.5%]). A BMI of ≥40 kg/m 2 was found to be significantly associated with PJI (hazard ratio [HR], 6.4; p < 0.001), reoperation (HR, 3.5; p < 0.001), and nonoperative complications (HR, 2.3; p = 0.018). Survivorship free of recurrent instability was 99.6% (95% CI, 99.4% to 99.8%) at 5 and 10 years, and the cumulative incidence of revision for instability was 0.14% at 5 years.

CONCLUSIONS

In one of the largest published series to date, survivorship following DAA THA was satisfactory at early to intermediate follow-up. The leading indications for revision were PJI, periprosthetic fracture, and aseptic loosening. Instability after DAA THA was uncommon and infrequently led to revision. As a note of caution, a BMI of ≥40 kg/m 2 was identified as a risk factor for adverse outcome after DAA THA.

LEVEL OF EVIDENCE

Therapeutic Level IV . See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

直接前路入路(DAA)是初次全髋关节置换术(THA)常用的手术入路。然而,DAA-THA的当代疗效仍需进一步阐明。因此,我们旨在描述DAA-THA术后的植入物生存率、并发症及临床疗效。

方法

从我们的多机构全关节登记系统中,确定了2010年至2019年间接受3698例初次DAA-THA手术的3184例患者。这些患者的平均年龄为65岁,平均体重指数(BMI)为29kg/m²,53%为女性。收集并分析翻修和再次手术的指征以及并发症的发生率。研究了包括年龄、性别、BMI以及手术量大与手术量小的外科医生等潜在风险因素。进行了描述性统计以及采用Cox回归分析的Kaplan-Meier生存率分析。

结果

初次DAA-THA术后10年,该队列无任何翻修的生存率为96%(95%置信区间[CI],95%至98%),无任何再次手术的生存率为94%(95%CI,92%至96%)。翻修的主要指征为假体周围关节感染(PJI)(n = 24;5年累积发生率,0.93%[95%CI,0.6%至1.5%])、假体周围骨折(n = 20;5年累积发生率,0.62%[95%CI,0.4%至1.0%])以及无菌性松动(n = 14;股骨11例,髋臼3例;5年累积发生率,0.84%[95%CI,0.5%至1.5%])。发现BMI≥40kg/m²与PJI(风险比[HR],6.4;p < 0.001)、再次手术(HR,3.5;p < 0.001)和非手术并发症(HR,2.3;p = 0.018)显著相关。5年和10年时无复发性不稳定的生存率为99.6%(95%CI,99.4%至99.8%),5年时因不稳定进行翻修的累积发生率为0.14%。

结论

在迄今为止发表的最大系列研究之一中,DAA-THA术后早期至中期随访的生存率令人满意。翻修的主要指征为PJI、假体周围骨折和无菌性松动。DAA-THA术后不稳定情况不常见,很少导致翻修。需要注意的是,BMI≥40kg/m²被确定为DAA-THA术后不良结局的一个风险因素。

证据水平

治疗性IV级。有关证据水平的完整描述,请参阅作者指南。

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