Yildirim Mustafa, Yildirim Zahide Sahin, Deniz Mustafa
Department of Anesthesiology and Reanimation, Bolu Izzet Baysal State Hospital, Bolu, Turkey.
Intensive Care Unit, Bolu Izzet Baysal State Hospital, Bolu, Turkey.
BMC Anesthesiol. 2024 Dec 23;24(1):473. doi: 10.1186/s12871-024-02866-2.
Nutritional deficiency is common in critically ill hospitalized patients. This condition may be aggravated by increased dietary requirements and deficiencies in nutrient absorption. This study aimed to evaluate the associations between the modified Nutritional Risk in Critically ill (mNUTRIC) score and mortality and morbidity in patients with sepsis.
In this prospective observational study, 78 patients with sepsis were enrolled in the general intensive care unit over a 3-month period. Demographic and clinical data and laboratory results were recorded and followed up. The nutrition of each patient was started by the nutrition team, and a modified score (mNUTRIC) was calculated. This score was used to assess the patients' nutritional status and mortality risk.
The mean age of the patients was 77.2 ± 9.9 years, and the majority were men. The median mNUTRIC score was 6. The cohort was divided into two groups: 31 patients (39.7%) with low scores and 47 patients (60.3%) with high mNUTRIC scores. A high mNUTRIC score was associated with an increased need for vasoactive drugs (p < 0.001) and mechanical ventilation (p < 0.001), as well as increased acute kidney injury (p = 0.014) and prolonged hospital stay (p < 0.001) during ICU follow-up. The mNUTRIC score showed high accuracy in predicting mortality (p < 0.001).
In this study, to predict the prognosis of patients with sepsis in the ICU, the mNUTRIC score was associated with mortality. The inclusion of nutritional assessment scoring tools in the routine clinical evaluation of ICU patients is important.
营养缺乏在重症住院患者中很常见。这种情况可能会因饮食需求增加和营养吸收不足而加重。本研究旨在评估改良的重症患者营养风险(mNUTRIC)评分与脓毒症患者死亡率和发病率之间的关联。
在这项前瞻性观察研究中,3个月内共有78例脓毒症患者入住综合重症监护病房。记录并随访人口统计学和临床数据以及实验室检查结果。每个患者的营养支持由营养团队启动,并计算改良评分(mNUTRIC)。该评分用于评估患者的营养状况和死亡风险。
患者的平均年龄为77.2±9.9岁,大多数为男性。mNUTRIC评分中位数为6分。该队列分为两组:31例(39.7%)低评分患者和47例(60.3%)高mNUTRIC评分患者。高mNUTRIC评分与血管活性药物需求增加(p<0.001)、机械通气需求增加(p<0.001)、急性肾损伤增加(p=0.014)以及重症监护病房随访期间住院时间延长(p<0.001)相关。mNUTRIC评分在预测死亡率方面显示出较高的准确性(p<0.001)。
在本研究中,为预测重症监护病房脓毒症患者的预后,mNUTRIC评分与死亡率相关。在重症监护病房患者的常规临床评估中纳入营养评估评分工具很重要。