Rayan G M, Gannaway J K, Pitha J, Dale G L
Clin Orthop Relat Res. 1985 Mar(193):299-307.
The effects of warm saline and heparinized autogeneic blood injection on a rat sciatic nerve were observed by histologic, histochemic, and CT planimetry. Demonstrable intraneural degenerative changes and epineurial cellular proliferation were present in both groups. Hemosiderin deposits were present in the epineurium and intraneurally only in the blood group. Epineurial saline injection produces nerve damage; therefore, its use for the purpose of neurolysis is not recommended. Further investigations are needed to study the effect of nonheparinized blood injection. The use of computerized planimetry in assessing quantitative nerve damage proved to be feasible.
通过组织学、组织化学和CT平面测量法观察温生理盐水和肝素化自体血注射对大鼠坐骨神经的影响。两组均出现明显的神经内退行性改变和神经外膜细胞增殖。仅在血液组的神经外膜和神经内出现含铁血黄素沉积。神经外膜注射生理盐水会造成神经损伤；因此，不建议将其用于神经松解目的。需要进一步研究来探讨非肝素化血液注射的效果。事实证明，使用计算机平面测量法评估定量神经损伤是可行的。
