Busabong Worathon, Songserm Nopparat, Woradet Somkiattiyos, Sripa Banchob
Department of Health Sciences, Faculty of Public Health, Ubon Ratchathani Rajabhat University, Ubon Ratchathani, Thailand.
Sisaket Provincial Public Health Office, Sisaket, Thailand.
Trop Med Int Health. 2025 Feb;30(2):99-107. doi: 10.1111/tmi.14073. Epub 2024 Dec 23.
Opisthorchis viverrini and cholangiocarcinoma have been recognised by the World Health Organisation as critical public health concerns, particularly in northeastern Thailand, where Opisthorchis viverrini is a significant cause of cholangiocarcinoma. This study examines the factors influencing Opisthorchis viverrini and cholangiocarcinoma prevention within the One Health framework in Kanthararom District, Sisaket Province, Thailand.
A cross-sectional study was conducted among 327 residents aged 20 and above, utilising a structured questionnaire to assess knowledge, attitudes, perceived self-efficacy and prevention behaviours. Data were analysed using descriptive statistics, Pearson's product-moment correlation coefficient and multiple regression analysis to identify relationships and predictors within the dataset.
The results showed that 53.52% of participants had moderate knowledge and attitudes towards prevention, while perceived self-efficacy was generally high. Positive correlations were found between income, knowledge, attitudes, self-efficacy and prevention behaviours. Key predictors of Opisthorchis viverrini and cholangiocarcinoma prevention behaviours included attitudes towards human health (β = 0.212), perceived self-efficacy in human health (β = 0.211), attitudes towards animal health (β = 0.205) and knowledge about human health (β = 0.138), accounting for 24.40% of the variance in prevention behaviours. These predictors were statistically significant at 0.05 (F = 25.95; p <0.001).
The findings suggest that enhancing knowledge, attitudes and self-efficacy is crucial to improving Opisthorchis viverrini and cholangiocarcinoma prevention. This study underscores the need for integrated public health strategies incorporating human, animal and environmental health to reduce the prevalence of Opisthorchis viverrini and cholangiocarcinoma in high-risk regions.
泰国宋卡府坎塔拉隆区的肝吸虫和胆管癌已被世界卫生组织认定为重大公共卫生问题，尤其是在泰国东北部，肝吸虫是胆管癌的一个重要病因。本研究在泰国四色菊府坎塔拉隆区的“同一健康”框架内，考察影响肝吸虫和胆管癌预防的因素。
对327名20岁及以上居民进行横断面研究，使用结构化问卷评估知识、态度、感知自我效能和预防行为。采用描述性统计、皮尔逊积差相关系数和多元回归分析对数据进行分析，以确定数据集中的关系和预测因素。
结果显示，53.52%的参与者对预防有中等程度的知识和态度，而感知自我效能普遍较高。收入、知识、态度、自我效能和预防行为之间存在正相关。肝吸虫和胆管癌预防行为的关键预测因素包括对人类健康的态度（β = 0.212）、对人类健康的感知自我效能（β = 0.211）、对动物健康的态度（β = 0.205）和对人类健康的知识（β = 0.138），占预防行为变异的24.40%。这些预测因素在0.05水平上具有统计学意义（F = 25.95；p < 0.001）。
研究结果表明，增强知识、态度和自我效能对于改善肝吸虫和胆管癌的预防至关重要。本研究强调需要采取综合公共卫生策略，将人类、动物和环境卫生纳入其中，以降低高危地区肝吸虫和胆管癌的患病率。
