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越南慢性风湿病患者使用非甾体抗炎药和皮质类固醇的知识、态度及实践:一项横断面研究

Knowledge, Attitude and Practice Regarding Nonsteroidal Anti-inflammatory Drugs and Corticosteroids Use Among Patients With Chronic Rheumatology Condition: A Cross-Sectional Study From Vietnam.

作者信息

Nguyen Hoa Thi Nhu, Nguyen Quan Manh, Ha Khuyen Thi Kim, Le Quynh Thi Nhu, Bui Binh Hai

机构信息

Rheumatology Department, VNU-University of Medicine and Pharmacy, Hanoi, Vietnam.

The Center of Rheumatology, Bach Mai Hospital, Hanoi, Vietnam.

出版信息

Clin Med Insights Arthritis Musculoskelet Disord. 2024 Dec 23;17:11795441241308876. doi: 10.1177/11795441241308876. eCollection 2024.

Abstract

OBJECTIVES

To identify gaps in knowledge, attitude, and practice regarding the use of corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs) among patients with chronic rheumatic diseases.

METHODS

A cross-sectional study was conducted using a questionnaire including 12 knowledge questions, 13 attitude assessment statements, 5 barrier assessment statements, and 7 practical scenarios. We counted the total numbers of correct answers in knowledge, positive attitudes, barriers, and appropriate practices and fitted using Poisson regression to examine factors associated with knowledge, attitudes, and practices.

RESULTS

A total of 182 participants were included in this study, a large proportion of them had never heard of corticosteroids (34%) and NSAIDs (54%) before. Physicians were the source of information regarding corticosteroids and NSAIDs in 83% and 84% of the cases, respectively. Gastric ulcer was the most commonly recognized adverse drug reaction (ADR) for corticosteroids (64%) and the only ADR recognized for NSAIDs (95%), while only few patients were aware of life-threatening ADRs. The primary barrier, with a 40% agreement, was health care providers' time constraints in providing medication information to patients. Our study findings did not reveal any gaps in practice, nor did they show any correlation between patients' knowledge and attitudes to the practice of using corticosteroids and NSAIDs.

CONCLUSION

There were gaps in knowledge, attitudes, and barriers to information access regarding NSAIDs and corticosteroid use in Vietnamese patients with chronic rheumatic diseases. Potential solutions include allocating more time for information exchange between physicians and patients, creating new channels to provide reliable information for patients, and emphasizing the important ADRs.

摘要

目的

识别慢性风湿性疾病患者在使用皮质类固醇和非甾体抗炎药(NSAIDs)方面的知识、态度和实践方面的差距。

方法

采用问卷调查进行横断面研究,问卷包括12个知识问题、13个态度评估陈述、5个障碍评估陈述和7个实际场景。我们计算了知识、积极态度、障碍和适当实践方面的正确答案总数,并使用泊松回归来检验与知识、态度和实践相关的因素。

结果

本研究共纳入182名参与者,其中很大一部分人以前从未听说过皮质类固醇(34%)和NSAIDs(54%)。分别有83%和84%的病例中,医生是关于皮质类固醇和NSAIDs的信息来源。胃溃疡是皮质类固醇最常被认可的药物不良反应(ADR)(64%),也是NSAIDs唯一被认可的ADR(95%),而只有少数患者意识到危及生命的ADR。主要障碍(40%的认同率)是医疗保健提供者在向患者提供用药信息方面的时间限制。我们的研究结果未揭示实践方面的任何差距,也未显示患者对使用皮质类固醇和NSAIDs的知识与态度之间存在任何相关性。

结论

越南慢性风湿性疾病患者在NSAIDs和皮质类固醇使用的知识、态度以及信息获取障碍方面存在差距。潜在的解决方案包括为医生和患者之间的信息交流分配更多时间、创建新的渠道为患者提供可靠信息以及强调重要的ADR。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c755/11664530/a978eade13eb/10.1177_11795441241308876-fig1.jpg

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