Xu Qian Ya, Sapana Tamang, Qi Yu, Fu Guo Wei, Guo Long Hui, Ma Wei, Wang Li Li, Zhao Gai, Wang Hai Xia, Zhang Qian
Department of Neonatal Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Henan, China.
Department of Cardiothoracic Vascular Surgery, The First Affiliated Hospital of Zhengzhou University, Henan, China.
Front Pediatr. 2024 Dec 9;12:1447418. doi: 10.3389/fped.2024.1447418. eCollection 2024.
Congenital tracheal stenosis (CTS) is a rare but life-threatening malformation of the trachea. Surgical reconstruction is the treatment of choice in symptomatic cases which is highly risky and is rarely performed in extremely premature infants. With this, reporting a case of CTS managed by tracheal reconstructive surgery under ECMO in a baby weighing 1.47 kg at 32 + 1 WOG was the first ever case in China.
A premature newborn with a very low birth weight (VLBW) was admitted to our institute for breathing difficulties, requiring mechanical ventilation, and experienced two unsuccessful attempts of extubation. The team performed tracheal reconstructive surgery supported by ECMO after identifying lower tracheal stenosis through a bronchoscopy examination. One month after the surgery, oxygen support was able to discontinue. The patient's entire hospitalization was incredibly challenging, marked by hemodynamic instability with persistent anemia, and disseminated intravascular coagulation (DIC), which were managed with great care. Despite the difficult stay, a follow-up bronchoscopy revealed no obstruction or tracheal stenosis, leading to a successful discharge.
Advancements in diagnostic techniques and innovative management methods have made diagnosing and treating CTS easier, even in premature infants. Our case is the first in China to successfully undergo tracheal reconstructive surgery supported by ECMO, inspiring future achievements in the medical field.
先天性气管狭窄(CTS)是一种罕见但危及生命的气管畸形。手术重建是有症状病例的首选治疗方法,风险很高,在极低体重早产儿中很少进行。鉴于此,报道一例32+1周胎龄、体重1.47 kg的婴儿在体外膜肺氧合(ECMO)支持下接受气管重建手术治疗CTS的病例,这在中国尚属首例。
一名极低出生体重(VLBW)的早产新生儿因呼吸困难入住我院,需要机械通气,且两次拔管尝试均未成功。通过支气管镜检查确定为低位气管狭窄后,该团队在ECMO支持下进行了气管重建手术。术后1个月,患者能够停止吸氧支持。患者的整个住院过程极具挑战性,其特点是血流动力学不稳定,伴有持续性贫血和弥散性血管内凝血(DIC),对此进行了精心处理。尽管住院过程艰难,但随访支气管镜检查显示无梗阻或气管狭窄,患者最终成功出院。
诊断技术的进步和创新的管理方法使CTS的诊断和治疗变得更加容易,即使是在早产儿中。我们的病例是中国首例在ECMO支持下成功进行气管重建手术的病例,为医学领域的未来成就带来了启发。