Kazarian Austin G, Ashbrook Caleb Q, Timmons Charles F, Peters Craig A, Schlomer Bruce J
Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Department of Pathology, UT Southwestern and Children's Medical Center, Dallas, TX, USA.
Urol Case Rep. 2024 Nov 19;58:102884. doi: 10.1016/j.eucr.2024.102884. eCollection 2025 Jan.
Sertoli cell tumors are a rare type of sex-cord stromal tumor. We present a case of a thirteen-year-old male presenting with 2-3 months of fevers and twenty-pound weight loss. Evaluation revealed leukocytosis, anemia, elevated systemic inflammatory markers and a negative infectious disease evaluation. An evaluation for malignancy revealed an incidental testicular mass. A radical orchiectomy lead to prompt resolution of fevers, leukocytosis, and elevated systemic inflammatory markers. Final pathology was consistent with a Sertoli cell tumor. To our knowledge, this is the first reported case of a Sertoli cell tumor presenting with fever, leukocytosis, and weight loss.
支持细胞肿瘤是一种罕见的性索间质肿瘤。我们报告一例13岁男性病例，该患者有2至3个月的发热症状，体重减轻了20磅。检查发现白细胞增多、贫血、全身炎症标志物升高，传染病评估结果为阴性。恶性肿瘤评估发现一例偶然的睾丸肿块。根治性睾丸切除术使发热、白细胞增多和全身炎症标志物升高的情况迅速得到缓解。最终病理结果与支持细胞肿瘤一致。据我们所知，这是首例报告的以发热、白细胞增多和体重减轻为表现的支持细胞肿瘤病例。
