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淋菌性角膜结膜炎继发角膜穿孔1例罕见病例

A Rare Case of Corneal Perforation Secondary to Gonococcal Keratoconjunctivitis.

作者信息

Che Ku Amran Che Ku Hafiza, Ngoo Qi Zhe, Awis Qarni Fadil

机构信息

Ophthalmology and Visual Science, Universiti Sains Malaysia, Kota Bharu, MYS.

Ophthalmology, Universiti Sains Malaysia, Kota Bharu, MYS.

出版信息

Cureus. 2024 Nov 23;16(11):e74312. doi: 10.7759/cureus.74312. eCollection 2024 Nov.

Abstract

Gonococcal keratoconjunctivitis (GKC) is an aggressive infection caused by , which can cause an acute, dreadful, ulcerative keratitis resulting in blindness if left untreated. We report a rare case of bilateral GKC complicated with left eye corneal perforation. A 20-year-old male presented with bilateral eye purulent discharge associated with vision loss over the left eye for two weeks prior to presentation. Gram stain from purulent discharge showed gram-negative diplococci and cultured positive for . Left eye corneal perforation was managed with cyanoacrylate glue and a bandage contact lens. Systemic and topical antibiotic treatments were administered. Resolution was achieved with the administration of one gram of intramuscular ceftriaxone in a single dose, and the patient had no recurrences. Prompt and effective antibiotic administration in the early stage of disease contributed to an adequate recovery in this case.

摘要

淋菌性角结膜炎(GKC)是由淋病奈瑟菌引起的一种侵袭性感染,若不治疗可导致急性、严重的溃疡性角膜炎,进而导致失明。我们报告一例罕见的双侧GKC合并左眼角膜穿孔病例。一名20岁男性就诊前两周出现双眼脓性分泌物,并伴有左眼视力下降。脓性分泌物革兰氏染色显示革兰氏阴性双球菌,培养结果为淋病奈瑟菌阳性。左眼角膜穿孔采用氰基丙烯酸酯胶水和绷带式隐形眼镜进行处理。给予全身及局部抗生素治疗。单次肌内注射1克头孢曲松后病情得到缓解,患者未复发。在疾病早期及时有效的抗生素治疗促成了该病例的充分康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe5/11666296/b9310aa38a91/cureus-0016-00000074312-i01.jpg

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