Gazet J C
Dis Colon Rectum. 1985 Feb;28(2):110-4. doi: 10.1007/BF02552659.
A variety of operations have been proposed for the treatment of radiation injuries of the rectum. In this study, the procedure advocated by the late Sir Alan Parks--resection of the diseased segment down to its points of fixation to the vagina, bladder or prostate; with perianal mucosal stripping of the anorectal segment and primary coloanal (pull-through) anastomosis--was performed in 11 patients. In two others, an attempt at colorectal anastomosis was abandoned because of extreme scarring in the pelvis. The procedures were done following definitive treatment of carcinoma of the rectum (seven patients), carcinoma of the cervix (two patients), carcinoma of the uterus (one patient), carcinoma of the ovary (one patient), seminoma (one patient), and carcinoma of the bladder (one patient). One patient died from a pulmonary embolus on the seventh postoperative day. Of the survivors with a coloanal anastomosis, all had successful closure of their temporary colostomies with follow-up from one to six years. In eight, continence was assessed as being good or excellent. Four patients required anastomotic dilation and another required a surgical procedure for anastomotic stricture. There was one instance each of reoperation for small bowel obstruction and ileocolic fistula. There were no instances of recurrence of hemorrhage, fistulas, perineal pain or tenesmus. The Parks procedure obviates the need for a difficult dissection of the lower rectum and separation of tissues damaged by radiation and avoids the need for eversion techniques. Its selective use is advocated for patients suffering from severe radiation injuries of the rectum.
针对直肠放射性损伤的治疗,人们提出了多种手术方法。在本研究中,11例患者接受了已故的艾伦·帕克斯爵士所倡导的手术——切除病变肠段直至其与阴道、膀胱或前列腺的固定点;同时对肛管直肠段进行肛周黏膜剥脱,并进行一期结肠肛管(拖出式)吻合术。另外2例患者,由于盆腔严重瘢痕形成,放弃了结肠直肠吻合术的尝试。这些手术是在对直肠癌(7例)、宫颈癌(2例)、子宫癌(1例)、卵巢癌(1例)、精原细胞瘤(1例)和膀胱癌(1例)进行确定性治疗之后进行的。1例患者在术后第7天死于肺栓塞。在接受结肠肛管吻合术的幸存者中,所有人的临时结肠造口均成功关闭,随访时间为1至6年。其中8例患者的控便能力评估为良好或优秀。4例患者需要进行吻合口扩张,另1例患者因吻合口狭窄需要接受手术治疗。小肠梗阻和回结肠瘘再次手术各有1例。没有出血、瘘管、会阴疼痛或里急后重复发的情况。帕克斯手术无需对低位直肠进行困难的解剖,也无需分离受辐射损伤的组织,并且避免了外翻技术的需要。对于患有严重直肠放射性损伤的患者,提倡选择性地使用该手术。