Tao Tiantian, Du Junni, Sun Yuyang, Li Xin, Chen Pingyu
Department of Pharmaceutical Regulatory Science and Pharmacoeconomics, School of Pharmacy, Nanjing Medical University, No.101 Longmian Road, Jiangning District, Nanjing, 211166, Jiangsu, China.
School of International Pharmaceutical Business, China Pharmaceutical University, No. 639 Longmian Road, Jiangning District, Nanjing, 211198, Jiangsu, China.
Int J Clin Pharm. 2025 Feb;47(1):31-45. doi: 10.1007/s11096-024-01846-3. Epub 2024 Dec 24.
Temporal discounting, the preference for immediate over delayed rewards, affects decision-making in domains like health and finance. Understanding the differences in how people discount health outcomes compared to monetary rewards is crucial to shaping health policy and technology assessments.
This systematic review and meta-analysis aimed to compare temporal discounting parameters between health outcomes and monetary rewards and evaluate their overall relationship.
Studies were retrieved from PubMed, Embase, Web of Science, and the Cochrane Library up to December 2023. Standardized mean differences (SMD) assessed discounting differences between statistical indicators, and correlation coefficients were transformed into Fisher's Z scores. Subgroup analyses based on population, tradability, magnitude, sign, and experimental process explored potential heterogeneity.
A total of 32 studies were included: 29 studies (47 pairs of health and money) for the comparative meta-analysis and 19 studies (32 pairs) for the correlation meta-analysis. No significant differences were found between health and money discounting, although the individuals were more patient with the health outcomes and more impulsive with the money. In the sign effect subgroup, health discounting for delayed losses was lower than for monetary losses (SMD: - 0.293; 95% CI: - 0.458, - 0.129). The pooled correlation coefficient (r) for all studies was 0.333 (95% CI: 0.283-0.383), indicating a moderate association. In subgroup analysis, when the indicator was the discount rate, the pooled r value for 16 studies was 0.278 (95% CI: 0.231, 0.325).
Although no significant statistical differences were found between health and money discounting, a moderate correlation was observed, supporting consistent discount rate settings for health technology assessments.
时间折扣,即对即时奖励而非延迟奖励的偏好,会影响健康和金融等领域的决策。了解人们在对健康结果进行折扣与对货币奖励进行折扣方面的差异,对于制定健康政策和技术评估至关重要。
本系统评价和荟萃分析旨在比较健康结果与货币奖励之间的时间折扣参数,并评估它们的总体关系。
截至2023年12月,从PubMed、Embase、Web of Science和Cochrane图书馆检索研究。标准化均数差(SMD)用于评估统计指标之间的折扣差异,相关系数转换为Fisher's Z分数。基于人群、可交易性、大小、符号和实验过程的亚组分析探讨了潜在的异质性。
共纳入32项研究:29项研究(47对健康与货币比较)用于比较荟萃分析,19项研究(32对)用于相关性荟萃分析。尽管个体对健康结果更有耐心,对货币更冲动,但在健康和货币折扣之间未发现显著差异。在符号效应亚组中,延迟损失的健康折扣低于货币损失(SMD:-0.293;95%CI:-0.458,-0.129)。所有研究的合并相关系数(r)为0.333(95%CI:0.283 - 0.383),表明存在中度关联。在亚组分析中,当指标为折扣率时,16项研究的合并r值为0.278(95%CI:0.231,0.325)。
尽管在健康和货币折扣之间未发现显著的统计学差异,但观察到中度相关性,支持在健康技术评估中设置一致的折扣率。