Varga G, Borbényi Z, István L, Szabó K, Nagy I, Kelényi G, Krizsa F, Cserháti I
Dtsch Med Wochenschr. 1985 Mar 1;110(9):328-32. doi: 10.1055/s-2008-1068822.
The effect of splenectomy was studied in 30 patients with non-Hodgkin lymphoma of low malignancy. Severe bacterial infections occurred in 9 patients. Follow-up of the total group of 72 patients-years revealed one infection requiring hospitalization per eight patient-years. With chronic lymphatic leukaemia there was no difference in the incidence of severe infection between splenectomized and non-splenectomized patients. In 12 patients the splenectomy produced favourable results in that in some (8) cytostatic treatment was no longer required, while in others (4) the dose of cytostatic drugs could be reduced after several months without any medication. Survival rate was not influenced by splenectomy.
对30例低恶性非霍奇金淋巴瘤患者进行了脾切除术效果的研究。9例患者发生了严重细菌感染。对72例患者年的总随访显示，每8个患者年就有1例感染需要住院治疗。对于慢性淋巴细胞白血病，脾切除患者和未脾切除患者的严重感染发生率没有差异。12例患者的脾切除术取得了良好效果，其中一些患者（8例）不再需要进行细胞抑制治疗，而其他患者（4例）在数月未用药后细胞抑制药物剂量可以减少。脾切除术对生存率没有影响。
