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[对需要血液透析的慢性肾脏病患者康复的建议(文献综述)]

[Recommendations for the rehabilitation of patients with chronic kidney disease requiring hemodialysis (literature review)].

作者信息

Badalov N G, Prilipko N S, Gameeva E V, Stepanova A M

机构信息

Federal Scientific and Clinical Center of Medical Rehabilitation and Balneology of the Federal Medical and Biological agency of Russia, Moscow, Russia.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia.

出版信息

Vopr Kurortol Fizioter Lech Fiz Kult. 2024;101(6):62-73. doi: 10.17116/kurort202410106162.

Abstract

UNLABELLED

Chronic kidney disease (CKD) is a global health problem, CKD is widespread in the world, on average it is detected in 10-13% of the adult population. Sedentary patients with CKD on dialysis have a higher risk of mortality. Despite the significant association of physical function with mortality in patients with CKD, physical function is not routinely assessed and exercise is not a component of the routine management of patients with CKD on dialysis.

OBJECTIVE

The purpose of this study was to evaluate the effectiveness of the influence of motor rehabilitation methods on the prognosis of patients with chronic kidney disease (CKD) using hemodialysis (HD) from the standpoint of evidence-based medicine according to a scientometric analysis of the literature.

MATERIAL AND METHODS

An analysis was carried out of systematic reviews (search depth 70 years) and network meta-analyses to assess the effectiveness of physical exercise, its intensity and duration, performed interdialytic and intradialytic in the rehabilitation of patients with CKD with renal failure requiring hemodialysis. We reviewed articles in foreign journals on the PubMed, Embase, CINAHL, Web of Science, Wan Fang data, Cochrane CENTRAL and Scopus platforms.

RESULTS

The use of different types of physical exercise with varying intensities and durations both during and outside of dialysis in CKD patients requiring hemodialysis has shown that aerobic exercise, resistance exercise and a combination of both are most effective in improving their physical condition and quality life. Meta-analyses provide evidence to support the value of intradialytic exercise compared with interdialytic exercise for dialysis patients. It is also noted that moderate-intensity exercise can be performed in various forms, both during and outside of dialysis, and the data studied demonstrate that moderate-intensity exercise best improves physical function.

CONCLUSION

Future large RCTs should pay more attention to rehabilitation and exercise programs for CKD patients requiring HD. To encourage inactive patients with CKD to engage in physical exercise, educating them about the effects of exercise is imperative. Accumulating evidence suggests that rehabilitation of patients with visceral disorders, such as renal, cardiac, and pulmonary disorders, can not only improve physical performance and quality of life, but also improve survival. Modern comprehensive rehabilitation of patients with CKD is aimed at prolonging life, which represents a new concept in renal rehabilitation.

摘要

未标注

慢性肾脏病(CKD)是一个全球性的健康问题,在世界范围内广泛存在,平均在10% - 13%的成年人口中被检测出。接受透析治疗的久坐不动的CKD患者死亡风险更高。尽管身体功能与CKD患者的死亡率有显著关联,但身体功能并未被常规评估,且运动也不是接受透析治疗的CKD患者常规管理的组成部分。

目的

本研究的目的是根据文献的科学计量分析,从循证医学的角度评估运动康复方法对接受血液透析(HD)的慢性肾脏病(CKD)患者预后的影响效果。

材料与方法

对系统评价(检索深度70年)和网状荟萃分析进行了分析,以评估在需要血液透析的肾衰竭CKD患者康复过程中,透析间期和透析期进行体育锻炼的效果、强度和持续时间。我们在PubMed、Embase、CINAHL、Web of Science、万方数据、Cochrane CENTRAL和Scopus平台上查阅了国外期刊上的文章。

结果

在需要血液透析的CKD患者中,在透析期间和透析间期使用不同类型、不同强度和持续时间的体育锻炼表明,有氧运动、抗阻运动以及两者结合在改善他们的身体状况和生活质量方面最有效。荟萃分析提供了证据,支持与透析间期运动相比,透析期运动对透析患者的价值。还指出,中等强度运动可以在透析期间和透析间期以各种形式进行,研究数据表明中等强度运动最能改善身体功能。

结论

未来的大型随机对照试验应更多地关注需要HD的CKD患者的康复和运动项目。为鼓励不活动的CKD患者进行体育锻炼,向他们宣传运动的效果势在必行。越来越多的证据表明,对患有内脏疾病(如肾脏、心脏和肺部疾病)的患者进行康复治疗,不仅可以提高身体机能和生活质量,还可以提高生存率。CKD患者的现代综合康复旨在延长生命,这代表了肾脏康复的一个新概念。

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