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约旦多囊卵巢综合征女性中补充和替代医学的使用:一项横断面研究。

Use of complementary and alternative medicine among females with polycystic ovary syndrome in Jordan: a cross-sectional study.

作者信息

Awwad Oriana, Saleh Mais, Bardaweel Sana, Alsamydai Ali, Afifi Fatma U, Akour Amal, Abu Tarboosh Renad, Hamdan Manar, Basha Asma Sa'd

机构信息

Department of Biopharmaceutics and Clinical Pharmacy, The University of Jordan, Amman, Jordan

University of Verona, Verona, Italy.

出版信息

BMJ Open. 2024 Dec 23;14(12):e088945. doi: 10.1136/bmjopen-2024-088945.

Abstract

BACKGROUND AND OBJECTIVES

Polycystic ovary syndrome (PCOS) is a prevalent female reproductive and metabolic disorder. Among patients with chronic conditions, an increasing number have approached complementary and alternative medicine (CAM) to cope with their disease. This study aimed to assess the use of CAM among females with PCOS in Jordan.

DESIGN, SETTINGS AND PARTICIPANTS: A cross-sectional study was conducted at one of the largest tertiary centres in Jordan. Adult females with PCOS were interviewed using a data collection tool.

OUTCOME MEASURES

CAM use and the factors associated with its use.

RESULTS

A total of 402 women participated in the study, the median-IQR age was 25 (31-21) years. Common PCOS signs/symptoms included menses irregularity (81.8%), fatigue (71.6%) and hyperandrogenism (77.6%). Among all participants, 63.2% used CAM with the most common being herbs (60.4%). The primary sources of information were family and friends (46.1%).Longer duration since diagnosis, having more PCOS signs/symptoms and a higher level of education were factors significantly associated with CAM use (=1.257, 95% CI=1.018 to 2.552, p=0.034; =1.146, 95% CI=1.052 to 1.250, p=0.002 and =1.584, 95% CI=1.054 to 2.379, p=0.027, respectively). Of all the CAM users, 57.5% reported an amelioration in PCOS symptoms; this was significantly associated with the long-term use of CAM (=12.759, 95% CI=6.789 to 23.976, p<0.001). Just a few participants (9.4%) reported side effects.

CONCLUSION

A variety of CAM approaches were reported by the study population; herbs were the most widely used and accepted by the patients. Considering the primary source of information and the potential interactions of herbal medicine with the standard PCOS treatment, efforts are needed by healthcare providers to better understand the use of CAM among their patients with PCOS.

摘要

背景与目的

多囊卵巢综合征(PCOS)是一种常见的女性生殖和代谢紊乱疾病。在慢性病患者中,越来越多的人采用补充和替代医学(CAM)来应对疾病。本研究旨在评估约旦PCOS女性对CAM的使用情况。

设计、地点与参与者:在约旦最大的三级医疗中心之一进行了一项横断面研究。使用数据收集工具对成年PCOS女性进行访谈。

观察指标

CAM的使用情况及其相关因素。

结果

共有402名女性参与研究,年龄中位数-IQR为25(31-21)岁。常见的PCOS体征/症状包括月经不规律(81.8%)、疲劳(71.6%)和高雄激素血症(77.6%)。在所有参与者中,63.2%使用CAM,最常用的是草药(60.4%)。信息的主要来源是家人和朋友(46.1%)。诊断后病程较长、有更多PCOS体征/症状以及受教育程度较高是与CAM使用显著相关的因素(分别为=1.257,95%CI=1.018至2.552,p=0.034;=1.146,95%CI=1.052至1.250,p=0.002;=1.584,95%CI=1.054至2.379,p=0.027)。在所有使用CAM的人中,57.5%报告PCOS症状有所改善;这与长期使用CAM显著相关(=12.759,95%CI=6.789至23.976,p<0.001)。只有少数参与者(9.4%)报告有副作用。

结论

研究人群报告了多种CAM方法;草药是患者使用最广泛且最易接受的。考虑到信息的主要来源以及草药与PCOS标准治疗的潜在相互作用,医疗服务提供者需要努力更好地了解其PCOS患者对CAM的使用情况。

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