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接受手术治疗的后天性间歇性和恒定性外斜视患者的临床特征。

Clinical features in patients with acquired intermittent and constant exotropia who underwent surgery.

作者信息

Akbari Mohammad Reza, Khorrami-Nejad Masoud, Azizi Elham, Masoomian Babak, Shakor Yasir Adil, Hadi Ali

机构信息

Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

BMC Ophthalmol. 2024 Dec 24;24(1):548. doi: 10.1186/s12886-024-03812-z.

Abstract

BACKGROUND

acquired exotropia mostly manifests as an intermittent form, and very few cases show constant exotrpia. However, the differences in the clinical features of the constant and intermittent exotropia patients has not been clear yet.

METHODS

We retrospectively evaluated 6159 patients with exotropia from 2012 to 2022 in Farabi Eye Hospital, Tehran, Iran. The preoperative data collected were best corrected distance visual acuity (BCVA), spherical equivalent refractive error, amount and laterality of exotropia, presence of amblyopia and anisometropia.

RESULTS

The mean age at the time of surgery was 21.9 ± 13.8 (range, 2-77) years and 3104 (50.4%) cases were male. Constant and intermittent exotropia were observed in 4244 (68.9%) and 1915 (31.1%) cases, respectively. BCVA was significantly worse in the constant than in the intermittent group (P < .05). In cases with dominancy, the non-dominant eye in intermittent exotropia patients showed significantly more minus spherical equivalent (-1.28 ± 3.03 diopter) compared to the constant group (-0.63 ± 4.41 diopter) (P < .001). Moreover, the mean angle of horizontal and vertical deviation at distance and near in patients with constant exotropia was significantly higher than in the intermittent cases, either when there was a dominance in one eye or in cases with no dominance (P < .001). Amblyopia was found in 38.3% of cases with constant and 13.1% with intermittent exotropia (P < .001). Anisometropia was observed in 821 (19.34%) with constant and 88 (4.6%) with intermittent exotropia (P < .001).

CONCLUSION

Constant exotropic patients had worse BCVA, larger angle of deviation, and higher prevalence of amblyopia and anisometropia compared to the intermittent cases.

摘要

背景

后天性外斜视大多表现为间歇性形式,极少病例表现为恒定性外斜视。然而,恒定性和间歇性外斜视患者的临床特征差异尚不清楚。

方法

我们回顾性评估了2012年至2022年在伊朗德黑兰法拉比眼科医院的6159例外斜视患者。收集的术前数据包括最佳矫正远视力(BCVA)、等效球镜屈光不正、外斜视的度数和方向、弱视和屈光参差的存在情况。

结果

手术时的平均年龄为21.9±13.8(范围2-77)岁,3104例(50.4%)为男性。分别在4244例(68.9%)和1915例(31.1%)中观察到恒定性和间歇性外斜视。恒定性外斜视组的BCVA明显比间歇性外斜视组差(P<0.05)。在有优势眼的病例中,间歇性外斜视患者的非优势眼等效球镜度数(-1.28±3.03屈光度)明显高于恒定性外斜视组(-0.63±4.41屈光度)(P<0.001)。此外,无论单眼有优势还是无优势,恒定性外斜视患者在远距离和近距离时的水平及垂直偏斜平均角度均明显高于间歇性外斜视患者(P<0.001)。恒定性外斜视病例中有38.3%发现有弱视,间歇性外斜视病例中有13.1%发现有弱视(P<0.001)。恒定性外斜视中有821例(19.34%)观察到屈光参差,间歇性外斜视中有88例(4.6%)观察到屈光参差(P<0.001)。

结论

与间歇性外斜视患者相比,恒定性外斜视患者的BCVA更差、偏斜角度更大,弱视和屈光参差的患病率更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fe8/11669212/33af646362fe/12886_2024_3812_Fig1_HTML.jpg

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