Srisajjakul Sitthipong, Prapaisilp Patcharin, Bangchokdee Sirikan
Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang road Bangkoknoi, Bangkok 10700, Thailand.
Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang road Bangkoknoi, Bangkok 10700, Thailand.
Eur J Radiol. 2025 Feb;183:111868. doi: 10.1016/j.ejrad.2024.111868. Epub 2024 Dec 2.
Bladder cancer is categorized into nonmuscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC), distinguished by the presence of detrusor muscle invasion. Urothelial cell carcinoma is the most common subtype of bladder cancer. Transurethral resection of bladder tumor (TURBT) is the standard approach for staging and managing NMIBC, while radical cystectomy remains the cornerstone treatment for MIBC. Multiparametric magnetic resonance imaging (mpMRI), comprising morphological imaging sequences (high-resolution T2-weighted images) and functional imaging sequences (dynamic contrast-enhanced images and diffusion-weighted images), serves as an ideal modality. It provides high-contrast resolution for visualizing bladder wall layers, thereby enabling proper and timely staging of bladder cancer. MRI can guide sampling resection and identify patients understaged after primary TURBT, facilitating appropriate surgical restaging. In 2018, the Vesical Imaging Reporting and Data System (VI-RADS), implementing a 5-point scale, was developed to standardize MRI protocols and reporting criteria-including tumor location, size, morphology, and invasiveness. The aim of this article is to navigate through all the steps to achieve VI-RADS assessment and to discuss practical pearls and pitfalls in the use of mpMRI. This approach can aid in pre-TURBT prediction of muscle invasion, representing an important asset in bladder cancer staging.
膀胱癌分为非肌层浸润性膀胱癌(NMIBC)和肌层浸润性膀胱癌(MIBC),二者的区别在于是否存在逼尿肌浸润。尿路上皮癌是膀胱癌最常见的亚型。经尿道膀胱肿瘤切除术(TURBT)是NMIBC分期和治疗的标准方法,而根治性膀胱切除术仍然是MIBC的基石性治疗方法。多参数磁共振成像(mpMRI)包括形态学成像序列(高分辨率T2加权图像)和功能成像序列(动态对比增强图像和扩散加权图像),是一种理想的检查方式。它能提供高对比度分辨率以显示膀胱壁各层,从而实现膀胱癌的准确及时分期。MRI可指导取材切除,并识别初次TURBT后分期过低的患者,有助于进行适当的手术再分期。2018年,膀胱影像报告和数据系统(VI-RADS)制定了一个5分制标准,用于规范MRI检查方案和报告标准,包括肿瘤位置、大小、形态和浸润情况。本文旨在梳理实现VI-RADS评估的所有步骤,并讨论使用mpMRI的实用技巧和陷阱。这种方法有助于在TURBT前预测肌肉浸润情况,是膀胱癌分期中的一项重要内容。