早产早期、中晚期及足月儿出生时和两个月时母体破伤风、白喉和百日咳抗体水平的衰减率
Decay Rates of Maternal Tetanus, Diphtheria, and Pertussis Antibody Levels in Early and Moderate-to-Late Preterm and Term Infants at Birth and at Two Months.
作者信息
Immink Maarten M, van der Maas Nicoline A T, Bekker Mireille N, de Melker Hester E, den Hartog Gerco, Rots Nynke Y, van Gageldonk Pieter G M, Groenendaal Floris, Sanders Elisabeth A M
机构信息
Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Department of Obstetrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, and Utrecht University, Utrecht, The Netherlands.
出版信息
Open Forum Infect Dis. 2024 Dec 10;12(1):ofae717. doi: 10.1093/ofid/ofae717. eCollection 2025 Jan.
A post hoc analysis of maternally derived antibodies at birth and age 2 months following second trimester maternal Tdap vaccination between 20 and 24 weeks' gestational age (GA) showed a faster decay rate of Tdap-related immunoglobulin G in early preterms born before 32 weeks' GA compared with moderate-to-late preterms and full-terms. This is different from previous studies and merits further research.
一项对孕中期20至24周胎龄（GA）时接受破伤风类毒素、白喉类毒素和无细胞百日咳疫苗（Tdap）接种的母亲所产生的出生时及2月龄抗体进行的事后分析显示，与中度至晚期早产儿和足月儿相比，孕32周前出生的极早早产儿中Tdap相关免疫球蛋白G的衰减速度更快。这与之前的研究不同，值得进一步研究。
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