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经导管电外科治疗瓣膜性心脏病的进展

Advances in Transcatheter Electrosurgery for Treating Valvular Heart Disease.

作者信息

Khan Jaffar M, Rogers Toby, Greenbaum Adam B, Babaliaros Vasilis C, Lisko John C, Yildirim Dursun Korel, Bruce Christopher G, Herzka Daniel A, Ratnayaka Kanishka, Lederman Robert J

机构信息

Cardiovascular Branch, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health Bethesda, MD.

Medstar Washington Hospital Center Washington, DC.

出版信息

US Cardiol. 2021 Mar 1;15:e03. doi: 10.15420/usc.2020.27. eCollection 2021.

Abstract

Delivery of electrosurgery energy through catheters and guidewires enables interventionists to 'cut' through obstructive intravascular lesions or across cardiac chambers. A novel application of transcatheter electrosurgery is to make controlled lacerations in heart valve leaflets. This review describes three applications of transcatheter electrosurgery of aortic and mitral valve leaflets to enable transcatheter heart valve implantation. Intentional laceration of the anterior mitral leaflet to prevent left ventricular outflow obstruction splits and splays the anterior mitral valve and enables transcatheter mitral valve replacement without left ventricular outflow tract obstruction. Technique modifications and novel applications are described. Bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction enables transcatheter aortic valve replacement without coronary artery obstruction. The technique is described and novel uses, especially in the setting of repeat transcatheter aortic valve replacement, are discussed. Finally, electrosurgical laceration and stabilization of mitral valve clip devices (ELASTA-Clip) enables transcatheter mitral valve replacement after MitraClip implantation. In conclusion, transcatheter electrosurgery is an important and versatile new tool in structural heart intervention.

摘要

通过导管和导丝输送电外科能量,使介入医生能够“切割”阻塞性血管内病变或穿过心脏腔室。经导管电外科的一种新应用是在心脏瓣膜小叶上进行可控撕裂。本综述描述了经导管电外科在主动脉瓣和二尖瓣小叶上的三种应用,以实现经导管心脏瓣膜植入。故意撕裂二尖瓣前叶以防止左心室流出道梗阻,可使二尖瓣前叶分裂和展开,从而在无左心室流出道梗阻的情况下进行经导管二尖瓣置换。文中描述了技术改进和新应用。故意撕裂生物人工或天然主动脉瓣叶以防止医源性冠状动脉梗阻,可在无冠状动脉梗阻的情况下进行经导管主动脉瓣置换。文中描述了该技术,并讨论了其新用途,特别是在重复经导管主动脉瓣置换的情况下。最后,二尖瓣夹装置的电外科撕裂和稳定(ELASTA-Clip)可在植入MitraClip后进行经导管二尖瓣置换。总之,经导管电外科是结构性心脏介入中一种重要且多功能的新工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c87e/11664758/c9464d35ea12/usc-15-e03-g001.jpg

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