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韩国残疾人中通过急诊科就诊的颗粒物暴露与住院情况:一项全国性病例交叉研究

PM and hospitalizations through the emergency department in people with disabilities: a nationwide case-crossover study in South Korea.

作者信息

Park Jinah, Kim Ayoung, Bell Michelle L, Al-Aly Ziyad, Ahn Seoyeong, Kim Sooyoung, Kwon Dohoon, Kang Cinoo, Oh Jieun, Kim Ho, Lee Whanhee

机构信息

Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, South Korea.

School of the Environment, Yale University, New Haven, USA.

出版信息

Lancet Reg Health West Pac. 2024 Dec 6;53:101256. doi: 10.1016/j.lanwpc.2024.101256. eCollection 2024 Dec.

Abstract

BACKGROUND

Little is known about the impact of PM on people with disabilities. We aimed to explore the association between PM and hospitalization via the emergency department (ED admission) among people with disabilities, together with the attributable ED admission cases and costs.

METHODS

We applied a time-stratified case-crossover design adjusting ozone, holiday, and temperature using seven years (2015-2021) of claim-based data on ED admissions from the Korean National Health Insurance Database. The analysis included all ED admission cases of beneficiaries with disabilities living in Korea (physical, intellectual, and mental disabilities; brain lesion disorders; blindness or vision loss; deafness or hearing loss; and autism) as well as selected controls without disabilities.

FINDINGS

There were 900,311 ED admissions among the 3,624,590 people with disabilities. The odds ratios of ED admissions associated with a 10 μg/m increase in PM were 1.039 (95% CI: 1.036-1.042) in people with disabilities and 1.022 (95% CI: 1.019-1.025) in people without disabilities. Individuals with mental disability, intellectual disability, and brain lesion disorder showed higher risk estimates compared to other disabilities. The risk estimates of ED admissions for cardiovascular and genitourinary diseases were more prominent among people with disabilities than those without disabilities.

INTERPRETATION

The impacts of PM on ED admissions was generally higher in the population with disabilities than those without disabilities, especially for certain causes of admission. These results could contribute to establishing targeted action plans including early warning system referring different threshold concentrations.

FUNDING

National Research Foundation.

摘要

背景

关于颗粒物(PM)对残疾人的影响,人们了解甚少。我们旨在探讨残疾人中PM与通过急诊科住院(急诊入院)之间的关联,以及可归因的急诊入院病例和费用。

方法

我们采用时间分层病例交叉设计,利用韩国国民健康保险数据库中七年(2015 - 2021年)基于索赔的急诊入院数据,对臭氧、节假日和温度进行调整。分析包括居住在韩国的残疾受益人的所有急诊入院病例(身体、智力和精神残疾;脑部病变疾病;失明或视力丧失;失聪或听力丧失;以及自闭症)以及选定的非残疾对照。

研究结果

在3624590名残疾人中,有900311例急诊入院。PM每增加10μg/m³,残疾人急诊入院的比值比为1.039(95%置信区间:1.036 - 1.042),非残疾人为1.022(95%置信区间:1.019 - 1.025)。与其他残疾相比,精神残疾、智力残疾和脑部病变疾病患者的风险估计更高。与非残疾人相比,残疾人中心血管疾病和泌尿生殖系统疾病急诊入院的风险估计更为突出。

解读

PM对急诊入院的影响在残疾人群体中通常高于非残疾人群体,尤其是对于某些入院原因。这些结果有助于制定有针对性的行动计划,包括参考不同阈值浓度的早期预警系统。

资金来源

国家研究基金会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3144/11667189/5c38d1dd7372/gr1.jpg

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