对吗啡成瘾患者进行眼部滴注纳洛酮会升高眼压：这可能是一种检测吗啡滥用情况的测试方法。

Ocular instillation of naloxone increases intraocular pressure in morphine-addicted patients: a possible test for detecting misuse of morphine.

作者信息

Drago F, Aguglia E, Dal Bello A, Panissidi G B, Bellomio F, Spampinato D, Gorgone G

出版信息

Experientia. 1985 Feb 15;41(2):266-7. doi: 10.1007/BF02002629.

DOI:10.1007/BF02002629

PMID:3972074

Abstract

The effect of conjunctival instillation of naloxone on intraocular pressure has been examined in morphine-addicted patients as compared to non-addicted healthy volunteers. Morphine-addicted subjects showed a lower basal value of intraocular pressure as compared to the control volunteers. The instillation of naloxone caused a normalization of intraocular pressure to a level similar to that of control volunteers. This test seems to be a useful screening method for detecting morphine addiction.

摘要

与未成瘾的健康志愿者相比，已对吗啡成瘾患者结膜滴注纳洛酮对眼压的影响进行了研究。与对照志愿者相比，吗啡成瘾受试者的眼压基础值较低。滴注纳洛酮使眼压恢复正常，达到与对照志愿者相似的水平。该测试似乎是检测吗啡成瘾的一种有用的筛查方法。