Nielsen T W, Holte M B, Berg-Beckhoff G, Thorn J J, Ingerslev J, Pinholt E M
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Esbjerg, Denmark; Department of Oral and Maxillofacial Surgery, University Hospital of Southern Denmark, Esbjerg, Denmark.
Research Unit for Health Promotion, Department of Public Health, Faculty of Health Sciences, University of Southern Denmark, Esbjerg, Denmark; Department of Research, University Hospital of Southern Denmark, Esbjerg, Denmark.
Int J Oral Maxillofac Surg. 2025 Jul;54(7):617-623. doi: 10.1016/j.ijom.2024.12.002. Epub 2024 Dec 24.
This study aimed to evaluate changes of the temporomandibular joint (TMJ) following maxillomandibular advancement surgery (MMA), long-term postoperative skeletal relapse, and progressive condylar resorption (PCR) development. Preoperative and postoperative cone beam computed tomography(2 weeks, 5 years) of 50 patients (33 female, 17 male; mean age 25.6 years) were assessed three-dimensionally. Compared to the preoperative state, the largest long-term changes of the TMJ were observed in the condyles: mean volume decrease of 9.94% for the right condyle and 8.35% for the left. Condylar volume changes contributed most to the changes in condylar height (effect size right/left, η = 0.71/0.72) and horizontal postoperative skeletal relapse (η = 0.22/0.20). In contrast, glenoid fossa and joint space changes were modest and unassociated with skeletal relapse. Five female patients (10%) showed signs of PCR, with a mean reduction in condylar volume of 32%, a significant loss of condylar height and skeletal relapse. In conclusion, at 5 years following MMA, mainly condylar volume changes were observed, which had the largest effect on long-term postoperative skeletal relapse when compared to glenoid fossa and joint space changes. PCR occurred in 10% of the patients and was related to a significant loss of condylar height and skeletal relapse.
本研究旨在评估上颌下颌前徙术(MMA)后颞下颌关节(TMJ)的变化、术后长期骨骼复发情况以及进行性髁突吸收(PCR)的发展。对50例患者(33例女性,17例男性;平均年龄25.6岁)术前及术后(2周、5年)的锥形束计算机断层扫描图像进行三维评估。与术前状态相比,TMJ长期变化最大的部位是髁突:右侧髁突平均体积减少9.94%,左侧减少8.35%。髁突体积变化对髁突高度变化(效应量右侧/左侧,η = 0.71/0.72)和术后水平向骨骼复发(η = 0.22/0.20)的影响最大。相比之下,关节窝和关节间隙变化较小,且与骨骼复发无关。5例女性患者(10%)出现PCR迹象,髁突体积平均减少32%,髁突高度显著降低且有骨骼复发。总之,MMA术后5年,主要观察到髁突体积变化,与关节窝和关节间隙变化相比,髁突体积变化对术后长期骨骼复发的影响最大。10%的患者发生PCR,且与髁突高度显著降低和骨骼复发有关。