在注射人绒毛膜促性腺激素当天血清孕酮水平升高会降低活产率吗？
Does elevated serum progesterone on the day of human chorionic gonadotropin administration decrease live birth rates?
作者信息
Humm K C, Ibrahim Y, Dodge L E, Hacker M R, Thornton K L, Penzias A S, Sakkas D
机构信息
Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, 330 Brookline Ave., KS 3, Boston, MA 02215, USA
Boston IVF, 130 Second Ave., Waltham, MA 02451, USA
出版信息
J Reprod Health Med. 2016 Dec;2(Suppl 2):S15-S18. doi: 10.1016/j.jrhm.2016.11.008. Epub 2016 Dec 29.
Abstract
The impact of elevated serum progesterone levels on pregnancy and live birth during in vitro fertilization (IVF) remains unclear. Our objective was to investigate whether elevated serum progesterone on the day of human chorionic gonadotropin (HCG) administration is associated with lower pregnancy and live birth rates. This mini review provides a synopsis of the literature in addition to some of our own data. On the whole pregnancy and live birth rates decrease with increasing progesterone on the day of HCG administration even after adjusting for confounders. The findings from the majority of manuscripts investigating this question appear to be in agreement.
摘要
血清孕酮水平升高对体外受精（IVF）期间妊娠和活产的影响仍不清楚。我们的目的是研究在注射人绒毛膜促性腺激素（HCG）当天血清孕酮升高是否与较低的妊娠率和活产率相关。这篇小型综述除了提供我们自己的一些数据外，还对相关文献进行了概述。总体而言，即使在对混杂因素进行调整后，HCG注射当天的妊娠率和活产率仍会随着孕酮水平的升高而降低。大多数研究这个问题的手稿得出的结果似乎是一致的。
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