• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

偶然发现的甲状腺结节的临床意义及负担。

The clinical significance and burden of thyroid nodules discovered incidentally.

作者信息

Dureja Rohil F, Casey Caoimhe, Barry Josephine, Tuthill Antoinette

机构信息

School of Medicine, University College of Cork, Cork, Ireland.

Endocrinology Department, Cork University Hospital, Wilton, Cork, Ireland.

出版信息

Ir J Med Sci. 2025 Feb;194(1):101-106. doi: 10.1007/s11845-024-03858-4. Epub 2024 Dec 26.

DOI:10.1007/s11845-024-03858-4
PMID:39724405
Abstract

BACKGROUND

The majority of thyroid nodules are benign; however current guidelines suggest that thyroid incidentalomas should be appropriately evaluated to rule out malignancy.

AIMS

This study aims to determine the incidence of thyroid incidentalomas and the likelihood that they harbour sinister pathology in the largest Irish cohort studied to-date.

METHODS

A retrospective observational chart review was conducted using data from July 2018 to December 2018 using the Radiology Database in use at Cork University Hospital. The text of 1000 imaging reports (500 carotid Doppler and 500 computed tomography thorax) was manually screened for phrases such as "thyroid mass" or "thyroid nodule".

RESULTS

On 1000 scans, 14 (1.4%) thyroid incidentalomas were discovered. The occurrence of incidentalomas by imaging was 2/500 (0.4%) for ultrasound and 12/500 (2.4%) for computed tomography. Three of these nodules (21.4%) were further evaluated with a subsequent ultrasound and due to a size of more than 1 cm underwent fine needle aspiration. Using the Thy classification, all three were given a Thy 2 (non-neoplastic) grading.

CONCLUSION

This study found that there was no clinical benefit to reporting the presence of thyroid incidentalomas incidentally noted on radiology investigations. Although the overall percentage of thyroid incidentalomas is low, this number may be enough to cause unnecessary strain on the healthcare system and burden patients with invasive investigations in addition to causing unnecessary anxiety.

摘要

背景

大多数甲状腺结节是良性的;然而,当前指南建议应对甲状腺偶发瘤进行适当评估以排除恶性肿瘤。

目的

本研究旨在确定甲状腺偶发瘤的发生率以及在爱尔兰迄今为止最大的队列研究中其存在恶性病变的可能性。

方法

利用科克大学医院使用的放射学数据库,对2018年7月至2018年12月的数据进行回顾性观察图表审查。人工筛查1000份影像报告(500份颈动脉多普勒检查和500份胸部计算机断层扫描)的文本,查找诸如“甲状腺肿物”或“甲状腺结节”等短语。

结果

在1000次扫描中,发现了14例(1.4%)甲状腺偶发瘤。通过影像学检查发现偶发瘤的情况为:超声检查2/500(0.4%),计算机断层扫描12/500(2.4%)。其中3个结节(21.4%)随后接受了超声复查,并因直径超过1厘米而接受了细针穿刺抽吸。根据Thy分类,这3个结节均被评为Thy 2(非肿瘤性)等级。

结论

本研究发现,报告放射学检查中偶然发现的甲状腺偶发瘤并无临床益处。尽管甲状腺偶发瘤的总体比例较低,但这个数字可能足以给医疗系统带来不必要的压力,并使患者承受侵入性检查的负担,此外还会引起不必要的焦虑。

相似文献

1
The clinical significance and burden of thyroid nodules discovered incidentally.偶然发现的甲状腺结节的临床意义及负担。
Ir J Med Sci. 2025 Feb;194(1):101-106. doi: 10.1007/s11845-024-03858-4. Epub 2024 Dec 26.
2
Benign and Malignant Thyroid Incidentalomas Are Rare in Routine Clinical Practice: A Review of 97,908 Imaging Studies.良性和恶性甲状腺偶发瘤在常规临床实践中罕见:对97908项影像学研究的综述
Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1327-31. doi: 10.1158/1055-9965.EPI-15-0292. Epub 2015 Jul 9.
3
Incidental thyroid nodules on COVID-19-related thoracic tomography scans: a giant cohort.新型冠状病毒肺炎相关胸部断层扫描中的偶然甲状腺结节:一项大型队列研究
Hormones (Athens). 2024 Jun;23(2):227-233. doi: 10.1007/s42000-023-00516-9. Epub 2023 Dec 16.
4
Prevalence, clinical and ultrasonographic characteristics of thyroid incidentalomas.甲状腺偶发瘤的患病率、临床及超声特征
Thyroid. 2004 Jan;14(1):29-33. doi: 10.1089/105072504322783812.
5
Thyroid Incidentalomas Detected on F-Fluorodeoxyglucose Positron Emission Tomography with Computed Tomography: Malignant Risk Stratification and Management Plan.甲状腺偶发瘤在 F-氟代脱氧葡萄糖正电子发射断层扫描与计算机断层扫描中的检测:恶性风险分层和管理计划。
Thyroid. 2018 Jun;28(6):762-768. doi: 10.1089/thy.2017.0560.
6
Reporting of Incidental Thyroid Nodules on Chest Computed Tomography and the Impact on Nodule Evaluation: A Retrospective Cohort Study.胸部计算机断层扫描中偶然发现的甲状腺结节报告及其对结节评估的影响:一项回顾性队列研究。
Thyroid. 2022 Dec;32(12):1529-1534. doi: 10.1089/thy.2022.0349. Epub 2022 Oct 31.
7
High prevalence of carcinoma in ultrasonography-guided fine needle aspiration cytology of thyroid nodules.甲状腺结节超声引导下细针穿刺细胞学检查中癌的高患病率。
Endocr J. 2008 Mar;55(1):135-42. doi: 10.1507/endocrj.k07-120. Epub 2008 Jan 24.
8
A risk-adapted approach using US features and FNA results in the management of thyroid incidentalomas identified by 18F-FDG PET.18F-FDG PET 发现的甲状腺偶发瘤采用美国特征和细针抽吸细胞学检查结果进行风险适应管理。
Ultraschall Med. 2014 Feb;35(1):51-8. doi: 10.1055/s-0033-1335328. Epub 2014 Jan 23.
9
Comparison of incidental versus palpable thyroid nodules presenting for fine-needle aspiration biopsy.偶然发现与可触及的甲状腺结节行细针穿刺活检的比较。
Head Neck. 2018 Jul;40(7):1508-1514. doi: 10.1002/hed.25132. Epub 2018 Mar 9.
10
Incidental Thyroid Nodules on Computed Tomography: A Systematic Review and Meta-Analysis Examining Prevalence, Follow-Up, and Risk of Malignancy.计算机断层扫描偶然发现的甲状腺结节:一项系统评价和荟萃分析,旨在探讨其患病率、随访情况以及恶性肿瘤风险。
Thyroid. 2024 Nov;34(11):1389-1400. doi: 10.1089/thy.2024.0313. Epub 2024 Sep 27.

本文引用的文献

1
The epidemiological landscape of thyroid cancer worldwide: GLOBOCAN estimates for incidence and mortality rates in 2020.全球甲状腺癌的流行病学概况:2020 年发病率和死亡率的 GLOBOCAN 估计。
Lancet Diabetes Endocrinol. 2022 Apr;10(4):264-272. doi: 10.1016/S2213-8587(22)00035-3. Epub 2022 Mar 7.
2
Prevalence of Thyroid Incidentalomas from 1995 to 2016: A Single-Center, Retrospective Cohort Study.1995年至2016年甲状腺偶发瘤的患病率:一项单中心回顾性队列研究。
J Endocr Soc. 2019 Nov 29;4(1):bvz027. doi: 10.1210/jendso/bvz027. eCollection 2020 Jan 1.
3
Evaluation and management of thyroid incidentalomas detected prior to the parathyroid surgery.
甲状旁腺手术前发现的甲状腺偶发瘤的评估与管理。
Surg Oncol. 2018 Sep;27(3):508-512. doi: 10.1016/j.suronc.2018.06.004. Epub 2018 Jun 11.
4
Clinically significant cancer rates in incidentally discovered thyroid nodules by routine imaging.通过常规成像偶然发现的甲状腺结节的临床显著癌症发生率。
J Surg Res. 2017 Nov;219:341-346. doi: 10.1016/j.jss.2017.06.050. Epub 2017 Jul 22.
5
Identification of benign and malignant thyroid nodules by in vivo iodine concentration measurement using single-source dual energy CT: A retrospective diagnostic accuracy study.使用单源双能CT通过体内碘浓度测量鉴别甲状腺良恶性结节:一项回顾性诊断准确性研究
Medicine (Baltimore). 2016 Sep;95(39):e4816. doi: 10.1097/MD.0000000000004816.
6
Endocrine incidentalomas.内分泌偶发瘤
Curr Probl Surg. 2016 May;53(5):219-46. doi: 10.1067/j.cpsurg.2016.04.001. Epub 2016 May 3.
7
Developing a Registry for Thyroid Incidentalomas: Lessons Learned and the Path Forward.建立甲状腺偶发瘤登记库:经验教训与未来之路
Thyroid. 2016 May;26(5):650-6. doi: 10.1089/thy.2015.0390. Epub 2016 Mar 30.
8
Benign and Malignant Thyroid Incidentalomas Are Rare in Routine Clinical Practice: A Review of 97,908 Imaging Studies.良性和恶性甲状腺偶发瘤在常规临床实践中罕见:对97908项影像学研究的综述
Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1327-31. doi: 10.1158/1055-9965.EPI-15-0292. Epub 2015 Jul 9.
9
Thyroid incidentalomas: epidemiology, risk stratification with ultrasound and workup.甲状腺偶发瘤:流行病学、超声风险分层及检查。
Eur Thyroid J. 2014 Sep;3(3):154-63. doi: 10.1159/000365289. Epub 2014 Sep 5.
10
Managing incidental thyroid nodules detected on imaging: white paper of the ACR Incidental Thyroid Findings Committee.影像检查中偶然发现的甲状腺结节的管理:美国放射学会偶然甲状腺发现委员会白皮书
J Am Coll Radiol. 2015 Feb;12(2):143-50. doi: 10.1016/j.jacr.2014.09.038. Epub 2014 Nov 1.