Yamamoto Yuki, Yoneda Akihiro, Miyazaki Osamu, Matsumoto Kimikazu, Yamagishi Satoko, Ichinose Akinori, Hirokawa Tomoya, Fujiogi Michimasa, Ishimaru Tetsuya, Shimojima Naoki
Division of Surgery, National Center for Child Health and Development, Tokyo, Japan.
Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
Pediatr Surg Int. 2024 Dec 26;41(1):47. doi: 10.1007/s00383-024-05956-x.
To assess the impact of the relationship between renal pedicles and tumors on surgical outcomes in patients with non-high-risk abdominal neuroblastoma.
We retrospectively analyzed cases of neuroblastoma without metastasis treated at our hospital between March 2002 and December 2023. Cases in which surgical resection was performed were divided into three groups according to imaging findings at the time of diagnosis and before surgery: Group E (tumor encasing renal pedicles), Group C (tumor in contact with renal pedicles), and Group S (tumor separated from renal pedicles).
Among 256 neuroblastoma cases diagnosed during the study period, 27 non-high-risk cases that underwent surgery for partial abdominal tumor resection or greater were included. The numbers of cases in the S group, C group, and E group, respectively, were 7, 9, and 11 at diagnosis, and 8, 14, and 5 before surgery. Renal complications (combined concurrent renal resection and post-operative renal atrophy) were seen in five E group cases at the time of diagnosis, and two C group cases and three E group cases preoperatively.
In non-high-risk abdominal neuroblastomas, tumors encased in the renal pedicles have the highest risk of renal complications, followed by tumors in contact with the renal pedicles.
评估肾蒂与肿瘤之间的关系对非高危腹部神经母细胞瘤患者手术结局的影响。
我们回顾性分析了2002年3月至2023年12月在我院接受治疗的无转移神经母细胞瘤病例。根据诊断时及手术前的影像学表现，将接受手术切除的病例分为三组：E组（肿瘤包绕肾蒂）、C组（肿瘤与肾蒂接触）和S组（肿瘤与肾蒂分离）。
在研究期间诊断的256例神经母细胞瘤病例中，有27例非高危病例接受了腹部部分肿瘤切除或更大范围的手术。诊断时S组、C组和E组的病例数分别为7例、9例和11例，手术前分别为8例、14例和5例。诊断时E组有5例出现肾脏并发症（合并同期肾切除和术后肾萎缩），术前C组有2例、E组有3例出现肾脏并发症。
在非高危腹部神经母细胞瘤中，包绕肾蒂的肿瘤发生肾脏并发症的风险最高，其次是与肾蒂接触的肿瘤。
