Guberinic Alis, Piet Berber, Meijer Frederick, Gijtenbeek Anja, Ter Laan Mark
Department of Neurosurgery, Radboud University Medical Center, Nijmegen, NLD.
Department of Pulmonology, Radboud University Medical Center, Nijmegen, NLD.
Cureus. 2024 Nov 26;16(11):e74468. doi: 10.7759/cureus.74468. eCollection 2024 Nov.
Patients with complex diseases are mostly treated in a multidisciplinary setting. The impact of multidisciplinary care cannot be emphasized enough as it has the potential to significantly increase survival and, in some cases, help avoid a risky treatment approach. The aim of this case illustration is to emphasize the importance of multidisciplinary treatment and learn from the different approaches that can be made while treating such patients. This case describes the clinical course of a 40-year-old female patient with metastatic non-small cell lung carcinoma (NSCLC), TNM classification cT3N3M1c. Although she had clinical and radiological signs of brain herniation, a risky neurosurgical intervention was prevented due to an extensive multidisciplinary approach. Moreover, the important role of multidisciplinary consultation, imaging, and tumor markers in identifying pseudoprogression in the increasingly complex treatment of metastatic NSCLC is also demonstrated. In conclusion, a multidisciplinary approach is a crucial step in the growing complex treatment strategies for patients with brain metastases of NSCLC.
患有复杂疾病的患者大多在多学科环境中接受治疗。多学科护理的影响再怎么强调也不为过，因为它有可能显著提高生存率，在某些情况下，有助于避免采用有风险的治疗方法。本病例说明的目的是强调多学科治疗的重要性，并从治疗此类患者时可采用的不同方法中学习。本病例描述了一名40岁转移性非小细胞肺癌（NSCLC）女性患者的临床病程，TNM分类为cT3N3M1c。尽管她有脑疝的临床和影像学体征，但由于广泛的多学科方法，避免了一次有风险的神经外科干预。此外，还展示了多学科会诊、影像学和肿瘤标志物在转移性NSCLC日益复杂的治疗中识别假性进展的重要作用。总之，多学科方法是NSCLC脑转移患者日益复杂的治疗策略中的关键一步。
